AI Article Synopsis

  • Petabytes of complex live cell and tissue imaging data are produced annually, offering significant potential to advance our understanding of biological processes at both the single-cell and multicellular levels.
  • Current analysis methods for these data are fragmented and tailored to individual users, which limits comprehensive analysis across various datasets and hinders scientific discoveries.
  • The authors propose a unified pipeline designed for the storage, segmentation, analysis, and statistical evaluation of live cell imaging datasets to enhance data analysis and insight generation.

Article Abstract

Petabytes of increasingly complex and multidimensional live cell and tissue imaging data are generated every year. These videos hold large promise for understanding biology at a deep and fundamental level, as they capture single-cell and multicellular events occurring over time and space. However, the current modalities for analysis and mining of these data are scattered and user-specific, preventing more unified analyses from being performed over different datasets and obscuring possible scientific insights. Here, we propose a unified pipeline for storage, segmentation, analysis, and statistical parametrization of live cell imaging datasets.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246344PMC
http://dx.doi.org/10.1042/BCJ20220053DOI Listing

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