Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196264 | PMC |
| http://dx.doi.org/10.3389/fpsyg.2022.833057 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Has AlphaFold3 achieved success for RNA?
Acta Crystallogr D Struct Biol
February 2025
Université Paris-Saclay, Université Evry, IBISC, 91020 Evry-Courcouronnes, France.
Predicting the 3D structure of RNA is a significant challenge despite ongoing advancements in the field. Although AlphaFold has successfully addressed this problem for proteins, RNA structure prediction raises difficulties due to the fundamental differences between proteins and RNA, which hinder its direct adaptation. The latest release of AlphaFold, AlphaFold3, has broadened its scope to include multiple different molecules such as DNA, ligands and RNA.
View Article and Find Full Text PDFAdvanced technologies in InGaN micro-LED fabrication to mitigate the sidewall effect.
Light Sci Appl
January 2025
Advanced Semiconductor Laboratory, Electrical and Computer Engineering Program, CEMSE Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
The size of InGaN micro-LEDs is continuously decreasing to meet the demands of various emerging applications, especially in tiny micro-displays such as AR/VR. However, the conventional pixel definition based on plasma etching significantly damages the mesa sidewalls, leading to a severe reduction in efficiency as the micro-LED size decreases. This seriously impedes the development and application of micro-LEDs.
View Article and Find Full Text PDFAnalysis on Salinity Tolerance of Lettuce Cultivars Under Saline Irrigation and Application of Organic Acids.
Plants (Basel)
January 2025
Department of Agrarian and Exact, Universidade Estadual da Paraíba, Catolé do Rocha 58884-000, PB, Brazil.
Freshwater depletion becomes a significant challenge as the population grows and food demand rises. We evaluated the responses of lettuce cultivars () under saline stress in photosynthetic responses, production, and ion homeostasis. We used a randomized block design in a 3 × 5 factorial scheme with five replications-the first factor: three cultivars of curly lettuce: SVR 2005, Simpson, and Grand Rapids.
View Article and Find Full Text PDFDiscovery of the First Efficacious Adenosine 2A Receptor Negative Allosteric Modulators for High Adenosine Cancer Immunotherapies.
J Med Chem
January 2025
School of Pharmaceutical Sciences, University of Geneva, 1206 Geneva, Switzerland.
Inhibition of the adenosine 2A receptor (AR) is recognized as a promising immunotherapeutic strategy but is challenged by the ubiquity of AR function in the immune system. To develop a safe yet efficacious immunotherapy, the discovery of a novel negative allosteric modulator (NAM) was preferred. Leveraging an in-house, sensitive, high-throughput screening cellular assay, novel AR NAM scaffolds were identified, followed by an extensive structure-activity relationship (SAR) study, leading to the discovery of potent 2-amino-3,5-dicyanopyridine derivatives.
View Article and Find Full Text PDFThe climate crisis and human health: identifying grand challenges through participatory research.
Lancet Glob Health
January 2025
Grand Challenges Canada, Toronto, ON, M5G 1M1, Canada.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!