The researchers are continuously working on nanomaterials and exploring many multidisciplinary applications in thermal engineering, biomedical and industrial systems. In current problem, the analytical simulations for performed for thermos-migration flow of nanofluid subject to the thermal radiation and porous media. The moving wedge endorsed the flow pattern. The heat source effects are also utilized to improves the heat transfer rate. The applications of thermophoresis phenomenon are addressed. The formulated set of expressions are analytically treated with implementation of variational iteration method (VIM). The simulations are verified by making the comparison the numerical date with existing literature. The VIM analytical can effectively tackle the nonlinear coupled flow system effectively. The physical impact for flow regime due to different parameters is highlighted. Moreover, the numerical outcomes are listed for Nusselt number.
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http://dx.doi.org/10.1038/s41598-022-14259-x | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
National Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.
TMEM16A, a key calcium-activated chloride channel, is crucial for many physiological and pathological processes such as cancer, hypertension, and osteoporosis, etc. However, the regulatory mechanism of TMEM16A is poorly understood, limiting the discovery of effective modulators. Here, we unveil an allosteric gating mechanism by presenting a high-resolution cryo-EM structure of TMEM16A in complex with a channel inhibitor that we identified, Tamsulosin, which is resolved at 2.
View Article and Find Full Text PDFKlin Monbl Augenheilkd
December 2024
Department für Augenheilkunde, Semmelweis Universität, Budapest, Ungarn.
Purpose: The aim of this study was to develop, optimise, train, and evaluate an algorithm for performing Supervised Automated Kinetic Perimetry (SAKP) using digitalised perimetric simulation data.
Methods: The original SAKP algorithm was based on findings from a multicentre study to establish reference values by semi-automated kinetic perimetry (SKP) combined with an automated examination method with moving stimuli ("Program K", developed in Japan). The algorithm evaluated the outer angles of isopter segments and responded to deviations from expected values by placing examination vectors to measure the outer boundaries of the visual field (VF).
Pain Med
November 2024
Pain Management Collaboratory Coordinating Center, Yale University, New Haven, CT, United States.
Mar Pollut Bull
November 2024
Zagazig University, Faculty of Science, Geology Department, Zagazig, Egypt.
Nowadays, oil spills threaten both aquatic and terrestrial environments, especially in regions with intensive oil refining and shipping activities and high environmental sensitivity, such as Alexandria city, Egypt. Oil spill characterization in coastal populous cities is particularly difficult due to large chemical/physical soil heterogeneities and saltwater intrusion, which represent a major challenges for soil remediation and restoration. Recently, the development of inversion algorithms enables electrical resistivity imaging (ERI) to perform detailed characterization of near-surface soil pollution.
View Article and Find Full Text PDFIntroduction: The employment of laparoscopic surgical techniques has reignited the debate on managing Meckel's Diverticulum (MD) due to its low complication rates. Nevertheless, concerns have been raised regarding completely removing any potential heterotopic mucosa. Our study aimed to compare surgical approaches in MD and assess the effectiveness of simple diverticulectomy.
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