Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications within the spatial biology field without neglecting accuracy.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203536 | PMC |
| http://dx.doi.org/10.1038/s41467-022-31110-z | DOI Listing |
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Nat Commun
June 2022
Department of Biomedical Engineering, Yale University, New Haven, CT, 06520, USA.
Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications within the spatial biology field without neglecting accuracy.
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