Aging of the face is a continuous and dynamic process that occurs due to changes in layers including skin, muscle, fat, and bone. There is an increasing patient preference toward nonsurgical techniques and procedures that require minimal downtime in all aspects of cosmetic surgery. The mainstay of treatment involves the administration of injectable fillers for temple volumization, eyebrow reshaping and forehead contouring, and neuromodulation to reduce the appearance of dynamic rhytids. Surgical and nonsurgical procedures can be used in combination in order to maximize periorbital rejuvenation. This article focuses on nonsurgical rejuvenation of the brow and periorbital complex.
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http://dx.doi.org/10.1016/j.cps.2022.03.004 | DOI Listing |
Hand Surg Rehabil
January 2025
Physical Therapy and Rehabilitation Unit, Policlinico di Modena, Modena, Italy; Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy.
A non-invasive thermoplastic orthosis combined with targeted exercise effectively addresses proximal interphalangeal joint (PIPj) stiffness. Stabilizing the metacarpophalangeal joint at 60 ° enables optimal torque transfer, improving flexion and correcting compensatory patterns. Posture maintenance prevents elastic recoil,enhancing tissue elongation.
View Article and Find Full Text PDFMed Image Anal
January 2025
Department of Mechanical and Metallurgical Engineering, School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile; Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile; Millennium Institute for Intelligent Healthcare Engineering, iHEALTH, Chile. Electronic address:
The identification of the Purkinje conduction system in the heart is a challenging task, yet essential for a correct definition of cardiac digital twins for precision cardiology. Here, we propose a probabilistic approach for identifying the Purkinje network from non-invasive clinical data such as the standard electrocardiogram (ECG). We use cardiac imaging to build an anatomically accurate model of the ventricles; we algorithmically generate a rule-based Purkinje network tailored to the anatomy; we simulate physiological electrocardiograms with a fast model; we identify the geometrical and electrical parameters of the Purkinje-ECG model with Bayesian optimization and approximate Bayesian computation.
View Article and Find Full Text PDFNeurology
February 2025
Department of Medicine and Geriatrics, Tuen Mun Hospital, Hong Kong, People's Republic of China.
Background And Objectives: Mitochondrial disorders are multiorgan disorders resulting in significant morbidity and mortality. We aimed to characterize death-associated factors in an international cohort of deceased individuals with mitochondrial disorders.
Methods: This cross-sectional multicenter observational study used data provided by 26 mitochondrial disease centers from 8 countries from January 2022 to March 2023.
Eur J Nucl Med Mol Imaging
January 2025
Institute of Radiation Medicine, Fudan University, Xietu Road 2094, Shanghai, 200032, China.
Objectives: Mesothelin (MSLN) is an antigen that is overexpressed in various cancers, and its interaction with tumor-associated cancer antigen 125 plays a multifaceted role in tumor metastasis. The serum MSLN expression level can be detected using enzyme-linked immunosorbent assay; however, non-invasive visualization of its expression at the tumor site is currently lacking. Therefore, the aim of this study was to develop a molecular probe for imaging MSLN expression through positron emission tomography (PET).
View Article and Find Full Text PDFInt J Cardiovasc Imaging
January 2025
Cardiovascular MR R&D, Siemens Medical Solutions USA, Inc., Chicago, IL, USA.
Parametric mapping has become a standard of care technique for the non-invasive assessment of myocardial edema and fibrosis. Conventional MOLLI-based T1 mapping is susceptible to many confounding effects particularly in the pediatric population. The requirement for compliant breath holds is a major limitation for younger or more ill patients.
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