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Evaluation of Hydatid Cyst Cases: A Single-center Retrospective Study.
Turkiye Parazitol Derg
January 2025
University of Health Sciences Türkiye, Kartal Dr. Lütfi Kırdar City Hospital, Clinic of Infectious Diseases and Clinical Microbiology, İstanbul, Türkiye.
Objective: Cystic echinococcosis (CE) is a zoonotic condition that can be encountered, particularly in developing countries, and leads to significant economic losses. This study was planned to observe the treatment options, complications, in the patients we followed.
Methods: Patients aged 18 and over who were diagnosed with hydatid cyst and followed in our hospital between January 2018 and December 2023 were included in the study.
Hydatid cysts, caused by the parasite, predominantly affect the liver and lungs, but can also impact other organs such as the kidneys, brain, and muscles. Infection occurs when individuals ingest eggs from contaminated food or water, leading to cyst formation primarily in the liver. While hydatid cysts are commonly found in various endemic regions, muscular involvement is rare, particularly in the psoas muscle.
View Article and Find Full Text PDFMechanisms of Nrf2 suppression and Camkk1 upregulation in Echinococcus granulosus-induced bone loss.
Int J Biol Macromol
February 2025
Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Beilin District, Xi'an, Shanxi Province 710000, China. Electronic address:
Osteoclast differentiation is essential for maintaining bone metabolism, and its dysregulation, particularly in the context of Echinococcus granulosus (CE) infection, can lead to severe bone loss. This study explores a novel mechanism by which CE protoscolices (PSC) drive osteoclast differentiation through the inhibition of Nrf2, followed by the upregulation of Camkk1. Transcriptome sequencing revealed a significant down-regulation of Nrf2 in cells treated with PSC.
View Article and Find Full Text PDF[A rare cause of multiple cavitary lung lesions].
Pneumologie
December 2024
Medizinische Klinik 5 (Pneumologie), Klinikum Fulda gAG, Campus Fulda, Universitätsmedizin Marburg, Fulda, Deutschland.
We report on a 32-year-old woman with multiple, progressive cavitary lung lesions. Lung cavities may occur in the context of various diseases and, thus, represent a huge diagnostic challenge. The spectrum of diseases comprises infections, systemic autoimmune rheumatic diseases, and malignancies.
View Article and Find Full Text PDFBioinformatic features and immunological response of recombinant antigen CTLA4-IgV-EgG1Y162 against Echinococcus granulosus.
Braz J Med Biol Res
November 2024
Department of Immunology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, Xinjiang, China.
Cystic echinococcosis (CE) is a zoonotic disease caused by the infection of Echinococcus granulosus (E. granulosus) larva. Currently, blocking the pathogenic cycle chain through immunoprophylaxis has become the main research direction.
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