Powered air-purifying respirator (PAPR) disinfection and risk of surface damage from hydrogen peroxide and quaternary ammonium chloride-based disinfectants.

Reusable Powered Air Purifying Respirators (PAPRs) have been increasingly used as an alternative to disposable masks or respirators for healthcare workers needing protection from respiratory droplets containing respiratory viruses, but little information is available concerning how well PAPRs resist damage from repeat disinfection over their lifetime. This study tested parts from four PAPRs against four commercially available hydrogen peroxide and quaternary ammonium chloride disinfectants by immersion for 28 days to simulate prolonged exposure. Risk of surface damage was assessed through color change, mass change, and visual observation of damage. Minimal risk of damage was found for three of the disinfectants tested and for the fourth disinfectant, a risk of surface damage to a small number of parts. Exposure to tap water caused similar damage in many cases. The study demonstrated that risk of surface damage varied by part and disinfectant, indicating that some disinfectants are more likely to be compatible against the wide range of materials and parts in a commercial PAPR and other disinfectants may show varying compatibility, with more risk to certain materials or parts.