AI Article Synopsis
- A new method for combining arylglycine derivatives and β-keto acids using visible light is introduced, allowing for the formation of γ-keto glycine derivatives.
- This reaction requires no photocatalysts or additives, making it a simple and efficient process conducted at room temperature.
- The text also discusses potential applications and suggests a possible mechanism behind the reaction.
Article Abstract
A visible-light-induced dehydrogenative/decarboxylative coupling reaction of arylglycine derivatives and β-keto acids is described. This photocatalyst- and additive-free protocol can be applied in the efficient synthesis of γ-keto glycine derivatives under ambient conditions. Further uses of this methodology and a plausible mechanism are also demonstrated.
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| http://dx.doi.org/10.1021/acs.joc.2c00149 | DOI Listing |
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