An important factor in house prices is its location. However, measurement errors arise frequently in the process of observing variables such as the latitude and longitude of the house. The single-index models with measurement errors are used to study the relationship between house location and house price. We obtain the estimators by a SIMEX method based on the local linear method and the estimating equation. To test the significance of the index coefficient and the linearity of the link function, we establish the generalized likelihood ratio (GLR) tests for the models. We demonstrate that the asymptotic null distributions of the established GLR tests follow -distributions which are independent of nuisance parameters or functions. Finally, two simulated examples and a real estate valuation data set are given to illustrate the effect of GLR tests.
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http://dx.doi.org/10.1080/02664763.2020.1754358 | DOI Listing |
Background: In AD trials, the treatment effect is typically evaluated by estimating the absolute difference in change from baseline to the end-of-study visit (e.g., 18 months) between treatment arms using the MMRM model.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Memory and Aging Center, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Background: Aging associates with decreased functional connectivity between brain regions linked to musical rhythm perception. Producing rhythmic music may result in strengthened functional connectivity of these regions, but more evidence is needed to support intervention design. Currently, few studies directly contrast younger and older adults' rhythmic music performance to understand brain-behavior relationships.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Neurobehavioral Systems, Inc, Berkeley, CA, USA.
Background: Paper-and-pencil neuropsychological tests have traditionally been considered the "gold standard" for clinical testing in AD/ADRD, but they have significant limitations: They are time-consuming, costly to administer, vulnerable to examiner bias and error, and unavailable to some patients due to location, transportation challenges, and cost. Manual tests also fail to comprehensively analyze many aspects of test performance. Computerized neuropsychological test batteries have been developed to address these shortcomings.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Cognitive Neurology, Montañeses, Buenos Aires, Argentina.
Background: LatAm-FINGERS - the first non-pharmacological multicenter randomized clinical trial in Latin America - is a valuable opportunity to study lifestyle in a heterogeneous and multiethnic population exposed to a large number of cardiovascular risk factors. Our aims are to study the risk distribution in the LatAm-FINGERS cohort and to explore the relationship between LIfestyle for BRAin Health (LIBRA) and cognition.
Method: We calculated the risk of dementia using the LIBRA score in the entire cohort (n = 1200).
Alzheimers Dement
December 2024
IPSIBAT (CONICET/National University of Mar del Plata), Mar del Plata, Buenos Aires, Argentina.
Background: In 2020, we developed LABPSI, a cognitive stimulation web lab. Usability analysis in MCI and healthy participants have already been studied, and currently, we performed it with acquired brain injuries (ABI) participants, as they can rehabilitate their cognitive symptoms and prevent the progression to dementia. Usability can be considered the ease of use of a certain product for a specific aim by a particular population.
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