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COVID-19 Increases the Risk of New Myocardial Infarction in Patients with Old Myocardial Infarction: A Retrospective Observational Study.
Clin Med Insights Cardiol
December 2024
Trauma Surgery Section, Hamad Medical Corporation, Doha, Qatar.
Background: We aimed to investigate the incidence of new acute myocardial infarction (AMI), in patients with Coronavirus disease (COVID-19) who had old MI. We hypothesized that COVID-19 increases the rate of repeated AMI in this population regardless of age and gender.
Methods: A retrospective analysis was conducted for adult patients admitted with COVID-19 and developed thromboembolic event (TEE) in 2020.
Association Between Peripheral Blood Regulatory T Cell Content with Inflammatory Stress Response and Immune Response in Children with Sepsis.
Mol Biotechnol
December 2024
Emergency Department, Shenzhen Baoan Wonmen's and Children's Hospital, Shenzhen, 518100, China.
The study aims to analyze the correlation between Regulatory T(Treg) Cells and inflammatory stress response and immune response in sepsis patients. Sixty sepsis patients admitted between January 2021 and June 2023 were selected as the subjects and included in the observation group. During the same period, 80 healthy children who underwent physical examinations in the hospital were included in the control group.
View Article and Find Full Text PDFPredicting survival in patients with SARS-CoV-2 based on cytokines and soluble immune checkpoint regulators.
Front Cell Infect Microbiol
December 2024
Department of Laboratory Medicine, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Seoul, Republic of Korea.
Background: Coronavirus disease 2019 (COVID-19) has been widespread for over four years and has progressed to an endemic stage. Accordingly, the evaluation of host immunity in infected patients and the development of markers for prognostic prediction in the early stages have been emphasized. Soluble immune checkpoints (sICs), which regulate T cell activity, have been reported as promising biomarkers of viral infections.
View Article and Find Full Text PDFAssociations between uric acid and depressive symptoms, and the mediating role of immunoinflammatory: Findings from rural older adults.
Brain Behav Immun Health
December 2024
School of Health Sciences, Western Sydney University, Sydney, Australia.
Article Synopsis
- The study focused on older adults in rural China and aimed to explore the link between uric acid levels, depressive symptoms, and inflammation.
- Conducted from January 2023 to April 2024, it involved 180 participants divided into two groups: 90 with depressive symptoms and 90 healthy controls.
- Results indicated that higher uric acid and C-reactive protein levels were associated with depressive symptoms, with specific findings for females, suggesting the need for further research on gender differences and potential treatments.
Analysis of Predictive Value of Cellular Inflammatory Factors and T Cell Subsets for Disease Recurrence and Prognosis in Patients with Acute Exacerbations of COPD.
Int J Chron Obstruct Pulmon Dis
November 2024
Department of Respiratory and Critical Care Medicine, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou City, Zhejiang Province, People's Republic of China.
Objective: To explore the predictive value of cellular inflammatory factors and T cell subsets for disease recurrence and prognosis in patients with acute exacerbations of chronic obstructive pulmonary disease (COPD).
Methods: Serum samples were collected from the two groups to detect and compare the levels of inflammatory cytokines [interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α)], T cell subsets (CD4+, CD8+), and clinical related indicators. Pearson correlation analysis was used to analyze the correlation between inflammatory cytokines, T cell subsets, and clinical indicators.
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