AI Article Synopsis
- The Ranson score, used to assess patients with acute pancreatitis, consists of 11 complicated parameters; this study aimed to simplify it.
- A study involving 938 acute pancreatitis patients led to the development of a revised Ranson score with nine parameters, which excluded one parameter and modified another.
- The revised score showed improved predictive ability for in-hospital mortality, with higher accuracy compared to the original score, but more validation through further studies is needed.
Article Abstract
Background: The Ranson score has 11 parameters that are complex and laborious to implement. In this study, we aimed to create a revised Ranson score by modifying the parameters in Ranson.
Methods: A total of 938 patients diagnosed with acute pancreatitis (AP) between 2014 and 2021 were included in the study. The parameters of the Ranson score were included in the univariate and multivariate analyses. According to the results, some of these parameters were modified, and then the revised Ranson score was created.
Results: The revised Ranson system was created with nine parameters by modifying the hematocrit parameter at 48 hours and excluding the aspartate aminotransferase parameter from the scoring system. For in-hospital mortality, the area under the curve value of the revised Ranson was 0.959 (95% CI: 0.931-0.986), and it was significantly higher compared to the three scoring systems evaluated. At a cut-off value of 3.5, the revised Ranson had a sensitivity and specificity of 91.7% and 89.1%, respectively, for mortality.
Conclusion: The revised Ranson scoring system had better predictive ability for all clinical outcomes compared to the original Ranson in our large sample of 938 patients. However, the revised version should be further validated by prospective and multicenter studies.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jhbp.1200 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pathology-Driven Automation to Improve Updating Documented Follow-Up Recommendations in the Electronic Health Record After Colonoscopy.
Clin Transl Gastroenterol
December 2024
Department of Health Informatics, NYU Langone Health, New York, New York, USA.
Introduction: Failure to document colonoscopy follow-up needs postpolypectomy can lead to delayed detection of colorectal cancer (CRC). Automating the update of a unified follow-up date in the electronic health record (EHR) may increase the number of patients with guideline-concordant CRC follow-up screening.
Methods: Prospective pre-post design study of an automated rules engine-based tool using colonoscopy pathology results to automate updates to documented CRC screening due dates was performed as an operational initiative, deployed enterprise-wide May 2023.
Anti-osteoporotic treatment reduces risk of revision following total shoulder arthroplasty in patients with osteoporosis.
J Shoulder Elbow Surg
November 2024
Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Background: Osteoporosis, a prevalent bone density disorder, introduces a complex dynamic in the context of total shoulder arthroplasty (TSA). However, despite the well-established association between osteoporosis and an elevated risk of revision, the existing literature lacks comprehensive insights into the impact of anti-osteoporotic therapy on surgical outcomes in the setting of TSA. Thus, the purpose of this study was to investigate whether anti-osteoporotic therapy correlates with improved revision outcomes following TSA.
View Article and Find Full Text PDFIncreased Risk of 10-Year Revision Following Total Hip Arthroplasty for Femoral Neck Fracture.
J Arthroplasty
September 2024
Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Article Synopsis
- * Researchers analyzed data from a national claims database and found that patients undergoing THA for FNF had significantly higher 10-year incidences of revision surgeries and complications like periprosthetic joint infections, dislocations, and mechanical loosening.
- * The findings indicate that femoral neck fractures pose greater risks for long-term complications post-surgery, suggesting the need for improved preoperative planning and postoperative care for affected patients.
An Investigation of Mortality Associated With Comorbid Pneumonia and Thrombocytopenia in a Rural Southwest Missouri Hospital System.
Cureus
August 2024
College of Medicine, Kansas City University, Joplin, USA.
Background: Pneumonia places a significant burden on individuals and society, contributing to a substantial number of hospital admissions, emergency department visits, deaths, and healthcare costs each year. Comorbidities can greatly increase the risk of poor outcomes when associated with pneumonia. One comorbidity that has yet to be thoroughly researched is thrombocytopenia, which is known to play an important role in activating the immune response to infections.
View Article and Find Full Text PDFLow free T3 level may predict the severity of acute pancreatitis.
Postgrad Med
June 2024
Internal Medicine Department, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Article Synopsis
- The study aimed to explore how changes in thyroid function tests can indicate the severity and prognosis of acute pancreatitis, even in patients with normal thyroid gland function.
- Conducted at a single center, the research analyzed patients diagnosed with acute pancreatitis and categorized them into two groups—those with healthy thyroid function (euthyroid) and those with Non-Thyroidal Illness Syndrome—which showed notable differences in thyroid hormone levels and established scoring systems.
- Results indicated that patients with Non-Thyroidal Illness Syndrome had lower free T3 levels and higher severity scores compared to the euthyroid group, suggesting that monitoring free T3 could enhance prognosis assessment for acute pancreatitis and potentially lower mortality rates.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!