The present investigation was undertaken to develop sauce from different cultivars of apples. Apple sauce of 5 cultivars was developed and effect of the storage conditions on the pH, acidity, TSS, total sugar, color, sensory, and rheological behavior of different apple sauce cultivars was studied. Analytical determinations were made after 0, 15, 30, and 45 days at both refrigerated and ambient conditions. The observed range of TSS was 30 to 30.14˚brix for refrigerated and 27.4 to 30.7˚brix for sauces stored at ambient storage conditions.. The pH decreased during the overall storage period from 4.07 to 3.96 in refrigerated samples, while as pH decreased from 4.06 to 3.92 in ambient stored samples. Rheological properties of sauces were evaluated using a parallel plate rheometer that showed the storage modulus, G' higher than the loss modulus, G″ for all the sauce samples indicating the dominance of the elastic behavior. The viscosity decreased with an increase in the shear rate for both, refrigerated and ambient stored sauce samples at the end of the storage period. Organoleptic characteristics (taste, color, aroma, and appearance) were examined by a semi-trained panelist using 5 point hedonic scale. The sauce samples from Mollies Delicious and Chamure apple cultivars showed the highest acceptance.
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http://dx.doi.org/10.1002/fsn3.2239 | DOI Listing |
Sci Adv
January 2025
Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Lysosomal storage diseases (LSDs) comprise ~50 monogenic disorders marked by the buildup of cellular material in lysosomes, yet systematic global molecular phenotyping of proteins and lipids is lacking. We present a nanoflow-based multiomic single-shot technology (nMOST) workflow that quantifies HeLa cell proteomes and lipidomes from over two dozen LSD mutants. Global cross-correlation analysis between lipids and proteins identified autophagy defects, notably the accumulation of ferritinophagy substrates and receptors, especially in and mutants, where lysosomes accumulate cholesterol.
View Article and Find Full Text PDFBiochem Genet
January 2025
Key Laboratory of Parasite and Vector Biology of the Chinese Ministry of Health, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Tropical Diseases, National Institute of Parasitic Diseases, Shanghai, 200025, People's Republic of China.
Drug resistance resulting from mutations in Plasmodium falciparum, that caused the failure of previously effective malaria drugs, has continued to threaten the global malaria elimination goal. This study describes the profiles of P. falciparum chloroquine resistance transporter (Pfcrt) and P.
View Article and Find Full Text PDFInterdiscip Sci
January 2025
Institute for Complexity Science, Henan University of Technology, Zhengzhou, 450001, China.
Artificial intelligence technology has demonstrated remarkable diagnostic efficacy in modern biomedical image analysis. However, the practical application of artificial intelligence is significantly limited by the presence of similar pathologies among different diseases and the diversity of pathologies within the same disease. To address this issue, this paper proposes a reinforced collaborative-competitive representation classification (RCCRC) method.
View Article and Find Full Text PDFCalcif Tissue Int
January 2025
Fondazione FIRMO Onlus, Italian Foundation for the Research On Bone Diseases, Florence, Italy.
Gaucher disease is a rare lysosomal storage disorder characterized by the accumulation of glucocerebroside lipids within multiple organs due to a deficiency of the lysosomal enzyme (acid β-glucosidase). It is an inherited autosomal recessive disease. The onset of symptoms can vary depending on disease type and severity, with milder forms presenting in adulthood.
View Article and Find Full Text PDFAm J Med Genet B Neuropsychiatr Genet
January 2025
Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
The RYR3 gene encodes a brain-type ryanodine receptor that functions to release calcium from intracellular storage and plays an essential role in calcium signaling. The associations between RYR3 variants and brain disorders remain unknown. We performed whole-exome sequencing in patients with idiopathic (non-lesional) partial epilepsy of unknown etiology.
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