Medlar () is an important fruit and is rich in nutritional and medical properties. Bioactive content and phenolic compounds of leaf, fruit, and seed samples of common medlar () and Stern's medlar () were studied. The coefficient of variation showed high values among all the characters and was more than 50.00%, ranging from 59.74 to 196.81%. The leaf of showed the highest total phenolic content (14.73 mg/g dry weight, DW) and followed by 13.70 mg/g DW in the seed of collected from Ilam province, Iran. The highest flavonoid content was observed in fruits of collected from the north of Iran (0.90 mg/g DW), and followed by the leaf of (0.53 mg/g DW). The phenolic compounds showed strong variation. Principal component analysis showed that four PCs explained 95.07% of the observed total variance. Ward dendrogram indicated two different clusters based on the characters measured, indicating high variation among the accessions. The current investigation clearly showed the potential value of the common medlar () and Stern's medlar () germplasm, as different medlar organs are significant sources of phenolic compounds and high antioxidant activity. Therefore, these species can be considered suitable sources of natural antioxidants, and may show potential future use in food and nutraceutical supplement formulations.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179139 | PMC |
http://dx.doi.org/10.1002/fsn3.2814 | DOI Listing |
J Sci Food Agric
January 2025
Department of Chemistry, Faculty of Science and Technology, Rajamangala University of Technology Thanyaburi, Thailand.
Background: Edible insects are used for consumption and traditional medicine due to their rich bioactive compounds. This study examined the bioactive compounds and inhibitory effects of crude extracts from Bombyx mori and Omphisa fuscidentalis on α-glucosidase, α-amylase, acetylcholinesterase (AChE), and tyrosinase. Fatty acids, including n-hexadecanoic acid and oleic acid, were identified in the extracts and evaluated for their inhibitory potential against the enzymes in vitro and in silico.
View Article and Find Full Text PDFSmall
January 2025
State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources, College of Chemistry, Xinjiang University, Urumqi, Xinjiang, 830017, P. R. China.
Developing simple and efficient extraction methods for phenolic substances from coal tar, which facilitate their direct transformation into high-performance electrode materials, holds considerable practical significance. In this study, amide-zinc chloride deep eutectic solvents are employed for efficient phenol extraction. The optimal phenol extraction process is subsequently investigated, and it is found that the robust hydrogen bonding interactions between solvents and phenols significantly enhance extraction efficiency.
View Article and Find Full Text PDFNutrients
December 2024
Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmacology and Toxicology, University of Florence, 50139 Florence, Italy.
Background: Oxaliplatin-induced neuropathy (OIN) is a severe painful condition that strongly affects the patient's quality of life and cannot be counteracted by the available drugs or adjuvants. Thus, several efforts are devoted to discovering substances that can revert or reduce OIN, including natural compounds. The carob tree, L.
View Article and Find Full Text PDFNutrients
December 2024
Instituto de Biomedicina de Sevilla, IBiS, Hospital Universitario Virgen Macarena, CSIC, Universidad de Sevilla, 41004 Sevilla, Spain.
Hyperhomocysteinemia (HHcy), characterized by elevated homocysteine (HCys) levels, is associated with increased risks of neurovascular diseases such as stroke or hydrocephalus. HHcy promotes oxidative stress, neuroinflammation, and endothelial dysfunction, disrupting the blood-brain barrier and accelerating neurodegeneration. These processes highlight HCys as both a biomarker and a potential therapeutic target in vascular-related neurological disorders.
View Article and Find Full Text PDFNutrients
December 2024
Orthodontics, Department of Conservative Odontology, Faculty of Dental Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.
Background: Inflammation-induced oxidative stress is a pathophysiological mechanism of inflammatory diseases. Treatments targeting oxidative stress can reduce inflammatory tissue damage.
Objectives: This study aimed to conduct phytochemical analysis and evaluate the antioxidant effects of the hydroalcoholic extract of blossoms () and rhizomes ().
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!