AI Article Synopsis
- The cover of the issue features Prof. Hamilton's group from New York University.
- The image illustrates how cucurbit[7]uril prevents the self-assembly of islet amyloid polypeptide, which is linked to cytotoxicity in insulin-producing cells.
- This research offers insights into protecting rat insulinoma cells from harmful protein assemblies, potentially impacting diabetes treatment.
Article Abstract
Invited for the cover of this issue is the group of Prof. Hamilton at New York University. The image depicts how cucurbit[7]uril inhibits islet amyloid polypeptide self-assembly that rescues rat insulinoma cells (a pancreatic β-cell model) from assembly-associated cytotoxicity. Read the full text of the article at 10.1002/chem.202200456.
Download full-text PDF |
Source |
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| http://dx.doi.org/10.1002/chem.202201698 | DOI Listing |
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