AI Article Synopsis
- The study investigated how excessive daytime sleepiness (EDS) affects health-related quality of life for patients with obstructive sleep apnea and their partners.
- A time trade-off method was used in a UK sample to measure utility values on a scale from 0 to 1, as participants evaluated the trade-off between time in a severely affected state versus full health.
- Results showed that both patients and partners experienced declining utility scores with increased severity of EDS, highlighting the significant negative impact on their quality of life.
Article Abstract
Study Objectives: This study aimed to quantify the impact of excessive daytime sleepiness (EDS) on patient and patient's partner health-related quality of life in the form of utility values typically used in health economic evaluations.
Methods: A time trade-off study was conducted in a UK general population sample (representing a societal perspective) to elicit utility values, measured on a 0 to 1 scale, for health states with varying obstructive sleep apnea-associated EDS severity. In a time trade-off study, health states are described, and participants "trade off" time in a specific higher severity state for a shorter amount of time in full health.
Results: Overall, the sample consisted of 104 participants, who were interviewed and took part in the time trade-off exercise to elicit utility values for patient and partner residual EDS health states. The average utility score declined with increasing obstructive sleep apnea-associated EDS severity for both patient (no EDS, 0.926; mild EDS, 0.794; moderate EDS, 0.614; severe EDS, 0.546) and partner (no EDS, 0.955; mild EDS, 0.882; moderate EDS, 0.751; severe EDS, 0.670) health states.
Conclusions: These results demonstrate the high impact that EDS in obstructive sleep apnea is estimated to have on patient and partner health-related quality of life.
Citation: Tolley K, Noble-Longster J, Mettam S, et al. Exploring the impact of excessive daytime sleepiness caused by obstructive sleep apnea on patient and partner quality of life: a time trade-off utility study in the UK general public. . 2022;18(9):2237-2246.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435341 | PMC |
| http://dx.doi.org/10.5664/jcsm.10092 | DOI Listing |
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