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STMGraph: spatial-context-aware of transcriptomes via a dual-remasked dynamic graph attention model.
Brief Bioinform
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Center for Genomics and Biotechnology, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, No. 15 Shangxiadian Road, Cangshan District, Fuzhou 350002, China.
Spatial transcriptomics (ST) technologies enable dissecting the tissue architecture in spatial context. To perceive the global contextual information of gene expression patterns in tissue, the spatial dependence of cells must be fully considered by integrating both local and non-local features by means of spatial-context-aware. However, the current ST integration algorithm ignores for ST dropouts, which impedes the spatial-aware of ST features, resulting in challenges in the accuracy and robustness of microenvironmental heterogeneity detecting, spatial domain clustering, and batch-effects correction.
View Article and Find Full Text PDFAssessing healthcare workers' knowledge and confidence in the diagnosis, management and prevention of Monkeypox.
World J Clin Cases
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Department of Dermatology, Cosmetology and Venereology, Shenzhen Hospital of Southern Medical University, Shenzhen 518101, Guangdong Province, China.
Background: Monkeypox (Mpox), is a disease of global public health concern, as it does not affect only countries in western and central Africa.
Aim: To assess Burundi healthcare workers (HCWs)s' level of knowledge and confidence in the diagnosis and management of Mpox.
Methods: We conducted a cross-sectional study an online survey designed mainly from the World Health Organization course distributed among Burundi HCWs from June-July 2023.
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Can J Psychiatry
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CHU Clermont-Ferrand, Psychiatrie B, Clermont-Ferrand F-63003, France.
Background: Although self-esteem is a relatively new concept, first developed in the field of social psychology, it has gained increasing importance in psychiatry, especially as a diagnostic criterion. However, it is poorly evaluated in clinical practice. The lack of an instrument allowing an easy global assessment may be the reason for this.
View Article and Find Full Text PDFEnhancing Construction Safety Through Workplace Surveillance and Systematic Follow-Ups.
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EHS Department, M&M SBG, L&T Construction (Larsen &Toubro), Kolkata, West Bengal, India.
Background: Globally, construction jobs are associated with serious occupational safety and health (OSH) risks. In large construction projects, managing OSH risks is challenging due to a multitude of factors, and it is important to have sound management strategies and innovative solutions to tackle these ever-evolving OSH risks. Safety surveillance plays a pivotal role in accident prevention in the construction industry.
View Article and Find Full Text PDFWhole-genome sequencing identifies novel loci for keratoconus and facilitates risk stratification in a Han Chinese population.
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National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China.
Background: Keratoconus (KC) is a prevalent corneal condition with a modest genetic basis. Recent studies have reported significant genetic associations in multi-ethnic cohorts. However, the situation in the Chinese population remains unknown.
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