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Enhanced recovery after surgery (ERAS) program in octogenarian patients: a propensity score matching analysis on the "Lazio Network" database. | LitMetric

AI Article Synopsis

  • - The study aimed to assess the safety and compliance of the Enhanced Recovery After Surgery (ERAS) protocol in patients aged 80 and above who underwent elective colorectal surgery in Italy from 2016 to 2018.
  • - A total of 1646 patients were analyzed, with a focus on 310 octogenarians, and results indicated similar surgical outcomes and ERAS compliance between older and younger patients, despite elderly patients experiencing more complications and longer hospital stays.
  • - Findings suggest that while the ERAS protocol is safe for octogenarians, they face a higher overall complication rate and longer recovery time compared to younger patients.

Article Abstract

Purpose: The aim of this study was to evaluate the safety and compliance with the enhanced recovery after surgery (ERAS) protocol in octogenarian patients undergoing colorectal surgery in 12 Italian high-volume centers.

Methods: A retrospective analysis was conducted in a consecutive series of patients who underwent elective colorectal surgery between 2016 and 2018. Patients were grouped by age (≥ 80 years vs < 80 years), propensity score matching (PSM) analysis was performed, and the groups were compared regarding clinical outcomes and the mean number of ERAS items applied.

Results: Out of 1646 patients identified, 310 were octogenarians. PSM identified 2 cohorts of 125 patients for the comparison of postoperative outcomes and ERAS compliance. The 2 groups were homogeneous regarding the clinical variables and mean number of ERAS items applied (11.3 vs 11.9, p-ns); however, the application of intraoperative items was greater in nonelderly patients (p 0.004). The functional recovery was similar between the two groups, as were the rates of postoperative severe complications and 30-day mortality rate. Elderly patients had more overall complications. Furthermore, the mean hospital stay was higher in the elderly group (p 0.027). Multivariable analyses documented that postoperative stay was inversely correlated with the number of ERAS items applied (p < 0.0001), whereas age ≥ 80 years significantly correlated with the overall complication rate (p 0.0419).

Conclusion: The ERAS protocol is safe in octogenarian patients, with similar levels of compliance and surgical outcomes. However, octogenarian patients have a higher rate of overall complications and a longer hospital stay than do younger patients.

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Source
http://dx.doi.org/10.1007/s00423-022-02580-yDOI Listing

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