An efficient and convenient method for the construction of diverse free (N-H)-benzazepinoindoles by Pd-catalyzed C(sp)-H imidoylative cyclization of 3-(2-isocyanobenzyl)-1-indoles was developed. The reaction shows a wide substrate scope and can be scaled up, providing a practical route to valuable bioactive azepinoindoles.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.joc.2c00717 | DOI Listing |
Publication Analysis
Top Keywords
pd-catalyzed csp-h
8
csp-h imidoylative
8
imidoylative cyclization
8
synthesis azepinoindoles
4
azepinoindoles pd-catalyzed
4
cyclization reactions
4
reactions efficient
4
efficient convenient
4
convenient method
4
method construction
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!