Modern robotic systems are expected to operate robustly in partially unknown environments. This article proposes an algorithm capable of controlling a wide range of high-dimensional robotic systems in such challenging scenarios. Our method is based on the path integral formulation of stochastic optimal control, which we extend with constraint-handling capabilities. Under our control law, the optimal input is inferred from a set of stochastic rollouts of the system dynamics. These rollouts are simulated by a physics engine, placing minimal restrictions on the types of systems and environments that can be modeled. Although sampling-based algorithms are typically not suitable for online control, we demonstrate in this work how importance sampling and constraints can be used to effectively curb the sampling complexity and enable real-time control applications. Furthermore, the path integral framework provides a natural way of incorporating existing control architectures as ancillary controllers for shaping the sampling distribution. Our results reveal that even in cases where the ancillary controller would fail, our stochastic control algorithm provides an additional safety and robustness layer. Moreover, in the absence of an existing ancillary controller, our method can be used to train a parametrized importance sampling policy using data from the stochastic rollouts. The algorithm may thereby bootstrap itself by learning an importance sampling policy offline and then refining it to unseen environments during online control. We validate our results on three robotic systems, including hardware experiments on a quadrupedal robot.
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http://dx.doi.org/10.1177/02783649211047890 | DOI Listing |
Sci Transl Med
January 2025
Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Oxygen is essential for human life, yet a growing body of preclinical research is demonstrating that chronic continuous hypoxia can be beneficial in models of mitochondrial disease, autoimmunity, ischemia, and aging. This research is revealing exciting new and unexpected facets of oxygen biology, but translating these findings to patients poses major challenges, because hypoxia can be dangerous. Overcoming these barriers will require integrating insights from basic science, high-altitude physiology, clinical medicine, and sports technology.
View Article and Find Full Text PDFNanophotonics
January 2025
MOE Key Laboratory of Advanced Micro-Structured Materials, School of Physics Science and Engineering Tongji University, Shanghai 200092, China.
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View Article and Find Full Text PDFEcol Evol
January 2025
Wildlife Research Division Environment and Climate Change Canada Ottawa Ontario Canada.
For birds breeding in the Arctic, nest success is affected by the timing of nest initiation, which is partially determined by local conditions such as snow cover. However, conditions during the non-breeding season can carry over to affect the timing of breeding. We used tracking and breeding data from 248 individuals of 8 species and subspecies of Arctic-breeding shorebirds to estimate how the timing of nest initiation is related to local conditions like snowmelt phenology versus prior conditions, measured by the timing and speed of migration.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2025
Paul. C. Lauterbur Research Centers for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Background: Brain temperature signifies the thermal homeostasis of the tissue, and may serve as a marker for neuroprotective therapy. Currently, it remains challenging to map the human brain temperature with high spatial resolution. The thermal dependence of chemical exchange saturation transfer (CEST) effects of endogenous labile protons may provide a promising mechanism for the absolute brain temperature imaging.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2025
School of Computer Science and Technology, Changchun University of Science and Technology, Changchun, China.
Background: Accurate segmentation of rib fractures represents a pivotal procedure within surgical interventions. This meticulous process not only mitigates the likelihood of postoperative complications but also facilitates expedited patient recuperation. However, rib fractures in computed tomography (CT) images exhibit an uneven morphology and are not fixed in position, posing difficulties in segmenting fractures.
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