Objectives: To evaluate the efficacy of computer-aided design/computer-aided manufacturing (CAD/CAM) technology in interventions implemented in orthodontics.
Methods: A scoping review of scientific evidence was accomplished, involving different databases. MesH terms and keywords were provided to examine clinical trials (CTs) in all languages. Exclusively CTs that fulfilled the eligibility criteria were admitted.
Results: Eight CTs were chosen. These experiments evaluated 542 patients. Four CTs compared the computer-aided indirect bonding method versus the traditional direct bonding of orthodontic brackets. Three CTs compared CAD/CAM retainers with other types of retainers, and one CT compared the CAD/CAM group with multistranded stainless steel wires versus stainless steel wires. Regarding the efficacy of the interventions with CAD/CAM technology used in orthodontics, variable results were found. The indirect bonded customized CAD/CAM brackets presented just a slight effect on the treatment efficacy and therapy results. Two CTs showed that an indirect bonding self-ligating standard system had a similar quality of therapy in comparison with the CAD/CAM customized bracket system. Concerning the clinical failure rate, no differences were presented between the CAD/CAM retainer and other retainers. A CAD/CAM system had more loose brackets than a noncustomized system and was observed also a greater amount of immediate debonding with CAD/CAM indirect bonding than with direct bonding. CAD/CAM fixed retainers revealed inferior relapse and fewer failures than lab-based and conventional chairside retainers. No changes between treatment groups were observed regarding the total therapy time, amount of appointments, and quantity of archwire bends.
Conclusions: In general terms, no greater efficacy of CAD/CAM technology was observed over traditional therapies used in orthodontics. However, it was found that gingival inflammation and the accumulation of bacterial plaque and dental calculus were lower when CAD/CAM retainers were used. When comparing interventions that include CAD/CAM systems with conventional therapies, no significant reduction in care times was found.
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http://dx.doi.org/10.1155/2022/5310555 | DOI Listing |
BMC Oral Health
January 2025
Department of Restorative Dentistry, Recep Tayyip Erdoğan University, Rize, Turkey.
Objectives: The aim of this systematic review and network meta-analysis was to compare the flexural strength of provisional fixed dental prostheses (PFDPs) fabricated using different 3D printing technologies, including digital light processing (DLP), stereolithography (SLA), liquid crystal display (LCD), selective laser sintering (SLS), Digital Light Synthesis (DLS), and fused deposition modeling (FDM).
Materials And Methods: A comprehensive literature search was conducted in databases including PubMed, Web of Science, Scopus, and Open Grey up to September 2024. Studies evaluating the flexural strength of PFDPs fabricated by 3D printing systems were included.
Sci Rep
January 2025
Division of Engineering, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.
This study advances microfluidic probe (MFP) technology through the development of a 3D-printed Microfluidic Mixing Probe (MMP), which integrates a built-in pre-mixer network of channels and features a lined array of paired injection and aspiration apertures. By combining the concepts of hydrodynamic flow confinements (HFCs) and "Christmas-tree" concentration gradient generation, the MMP can produce multiple concentration-varying flow dipoles, ranging from 0 to 100%, within an open microfluidic environment. This innovation overcomes previous limitations of MFPs, which only produced homogeneous bioreagents, by utilizing the pre-mixer to create distinct concentration of injected biochemicals.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Anatomy, Nihon University School of Dentistry, Tokyo, Japan.
This study presents a novel method for creating customized brain slice matrices using Computer-Aided Design (CAD) and 3D printing technology. Brain Slice Matrices are essential jigs for the reproducible preparation of brain tissue sections in neuroscience research. Our approach leverages the advantages of 3D printing, including design flexibility, cost-effectiveness, and rapid prototyping, to produce custom-made brain matrices based on specific morphometric measurements.
View Article and Find Full Text PDFOral Maxillofac Surg
January 2025
Research Center for Digital Technologies in Dentistry and CAD/CAM, Department of Dentistry, Faculty of Medicine and Dentistry, Danube Private University, Steiner Landstraße 123, Krems an der Donau, 3500, Austria.
Purpose: Precise implant placement is essential for optimal functional and aesthetic outcomes. Digital technologies, such as computer-assisted implant surgery (CAIS), have improved implant outcomes. However, conventional methods such as static and dynamic CAIS (dCAIS) require complex equipment.
View Article and Find Full Text PDFLab Chip
January 2025
Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.
Organ-on-a-chip culture systems using human organ tissues provide invaluable preclinical insights into systemic functions . This study aimed to develop a novel human testicular tissue chip within a microfluidic device employing computer-aided design software and photolithography technology. Polydimethylsiloxane was used as the primary material to ensure marked gas permeability and no biotoxicity, enabling effective mimicry of the testicular microenvironment.
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