is a tropical plant that is widely used in Asian folk medicine. Little is known about the alpha-glucosidase inhibition and antimicrobial properties of compounds from this plant. In the present study, the phytochemical study of the aerial parts of collected in Vietnam was conducted using multiple chromatographic methods. The chemical structures of isolated compounds were identified by comprehensive spectroscopic methods. Two new compounds, berectone C () and ()-tetracosyl 3-(3-hydroxy-4-methoxyphenyl)acrylate (), together with the known compounds boeravinone C (), liquiritigenin (), bis(1-indol-3-yl)methanone (), and indole-3-carboxylic acid () were isolated and structural elucidated. Compounds and were evaluated for alpha-glucosidase inhibition and antimicrobial activity against antibiotic-resistant, pathogenic bacteria , and . Compound showed strong inhibition of the alpha-glucosidase enzyme (IC 43 µg/mL). Only compound exhibited antimicrobial property against , forming an inhibition zone of 11 mm.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/14786419.2022.2086543 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!