Aim: This research work aims at developing an automatic medical image analysis and detection for accurate classification of brain tumors from a magnetic resonance imaging (MRI) dataset. We developed a new MIDNet18 CNN architecture in comparison with the AlexNet CNN architecture for classifying normal brain images from brain tumor images.
Materials And Methods: The novel MIDNet18 CNN architecture comprises 14 convolutional layers, seven pooling layers, four dense layers, and one classification layer. The dataset used for this study has two classes: normal brain MR images and brain tumor MR images. This binary MRI brain dataset consists of 2918 images as the training set, 1458 images as the validation set, and 212 images as the test set. The independent sample size calculated was seven for each group, keeping GPower at 80%.
Result: From the experimental performance metrics, it could be inferred that our novel MIDNet18 achieved higher test accuracy, AUC, F1 score, precision, and recall over the AlexNet algorithm.
Conclusion: From the result, it can be concluded that MIDNet18 is significantly more accurate (independent sample t-test <0.05) than AlexNet in classifying tumors from brain MRI images.
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http://dx.doi.org/10.47750/jptcp.2022.898 | DOI Listing |
PLoS One
January 2025
Department of Biology, West Virginia State University, Institute, WV, United States of America.
Glioblastoma multiforme (GBM), the most prevalent primary malignant brain tumor in adults, exhibits a dismal 6.9% five-year survival rate post-diagnosis. Thymoquinone (TQ), the most abundant bioactive compound in Nigella sativa, has been extensively researched for its anticancer properties across various human cancers.
View Article and Find Full Text PDFJ Neurooncol
January 2025
Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.
Background: Medulloblastoma is the most commonly occurring malignant brain tumor of childhood. Treatment includes a combination of surgery, radiation therapy, and chemotherapy, all of which are associated with cognitive impairments. Despite appreciation of the value of neuropsychological evaluations to assess for cognitive impairments, there are barriers to these evaluations.
View Article and Find Full Text PDFNeurosurg Rev
January 2025
Department of Neurosurgery, Korea University Guro Hospital, Korea University Medical College, Seoul, Korea.
Introduction: Craniopharyngiomas are challenging benign tumors arising from Rathke's pouch remnants, often requiring multidisciplinary management due to their proximity to critical neurovascular structures. This meta-analysis systematically compares conventional radiation therapy (RT) and stereotactic radiosurgery (RS) in treating residual or recurrent craniopharyngiomas.
Method: A comprehensive literature search identified 44 studies, including 46 reports, meeting inclusion criteria such as progression-free survival (PFS) and post-radiotherapy complications.
Front Aging Neurosci
January 2025
School of Medicine, Yunnan University, Kunming, China.
Background: Traumatic brain injury (TBI) can generally be divided into focal damage and diffuse damage, and neonate Hypoxia-Ischemia Brain Damage (nHIBD) is one of the causes of diffuse damage. Patients with nHIBD are at an increased risk of developing Alzheimer's disease (AD). However, the shared pathogenesis of patients affected with both neurological disorders has not been fully elucidated.
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