Purpose: To determine whether severity of periorbital necrotizing fasciitis can be predicted based on premorbid patient characteristics.
Methods: Records of 10 consecutive patients with periorbital necrotizing fasciitis presenting at a single center, treated by one attending ophthalmic plastic surgeon, were retrospectively reviewed. Demographic information and medical history were used to determine a Charlson Comorbidity Index (CCI) score for each patient. Other variables included presenting visual acuity, number of surgical debridements performed, infectious organism (if known), and visual acuity at last follow-up. Data were compared with Mann-Whitney U test to determine correlation between variables, using -values as outcome measures.
Results: Increased age at presentation correlated with worse presenting and final visual acuity, requiring more surgical debridements to control disease (each < .0001). Worse initial visual acuity correlated with need for increased number of debridements ( = .002), but increased number of debridements did not correlate with final visual acuity ( = .101). CCI did not correlate with initial vision ( = .30), final vision ( = .72), or number of surgical debridements necessary ( = .99). Presenting visual acuity did not correlate with final visual acuity ( = .268).
Conclusion: Older patients have more severe cases of periorbital necrotizing fasciitis, as defined by increased number of surgeries required to control disease and worse visual outcomes. CCI did not correlate with severity of disease.
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http://dx.doi.org/10.1080/01676830.2022.2087231 | DOI Listing |
Ophthalmic Plast Reconstr Surg
January 2025
Department of Ophthalmology and Visual Sciences, University of Michigan W.K. Kellogg Eye Center, Ann Arbor, Michigan, U.S.A.
A 54-year-old female with myelodysplastic syndrome on chemotherapy presented with 10 days of periocular erythema and edema worsening on oral antibiotics. Computed Tomography scan showed periorbital soft tissue swelling without postseptal extension or abscess. Intravenous broad-spectrum antibiotics were administered.
View Article and Find Full Text PDFOphthalmic Plast Reconstr Surg
December 2024
Department of Ophthalmology, Lions Eye Institute.
Purpose: Periorbital necrotizing fasciitis (NF) and sinusitis-related orbital cellulitis (OC) present with common clinical features, although the management algorithms for these ailments vary considerably. Previous investigations have failed to identify biomarkers that distinguish between these entities. This study was designed to explore the role of the derived neutrophil-to-lymphocyte and neutrophil-to-platelet ratios in discerning NF from OC.
View Article and Find Full Text PDFBMJ Case Rep
December 2024
Surgery, Shri BM Patil Medical College Hospital and Research Centre, Vijayapura, Karnataka, India.
J Fr Ophtalmol
December 2024
Edward Harkness Eye Institute, Department of Ophthalmology, Columbia University Irving Medical Center, New York, NY, United States. Electronic address:
Objective: Hyperbaric oxygen therapy (HBOT) has emerged as a versatile tool in the management of an array of medical conditions, including tissue ischemia and delayed wound healing. Despite the incorporation of HBOT in other medical fields, HBOT is not routinely utilized in the field of ophthalmic plastic and reconstructive periorbital surgery.
Design: Case series.
Exp Eye Res
December 2024
Department of Ophthalmology, The Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Tear inflammatory cytokines are a novel biomarker studied in a range of ocular surface diseases, periorbital and orbital conditions. This single-centre prospective study between 2022 and 2024 aims to characterise tear cytokine profiles (Interleukin-1β [IL-1β], IL-2, IL-6, Interferon-γ [IFN-γ] and Tumour Necrosis Factor-α [TNF- α]) in orbital inflammatory disease (OID). OID patients had pre-treatment tear collection via micropipette, and cytokine analysis via multiplex bead array analysis.
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