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[Prevalence of dengue fever in patients with febrile syndrome at the Sylvanus Olympio Teaching Hospital of Lomé (Togo) in 2017]. | LitMetric

[Prevalence of dengue fever in patients with febrile syndrome at the Sylvanus Olympio Teaching Hospital of Lomé (Togo) in 2017].

Med Trop Sante Int

Faculté des sciences de la santé (FSS), Département des sciences pharmaceutiques, Laboratoire de biologie et d'immunologie (BIOLIM), Département des sciences fondamentales, Université de Lomé, Togo.

Published: December 2021

AI Article Synopsis

  • This study investigates the prevalence of dengue fever among patients with febrile syndrome at a hospital in Lomé, Togo, where data on this disease is limited.
  • Out of 147 patients, dengue fever was found in 17% of cases, while malaria had a prevalence of 10.2%.
  • The study demonstrated a significant agreement between two testing methods for dengue, indicating that dengue fever is a notable cause of febrile illness in the region, similar to malaria.

Article Abstract

Aims: Dengue is the most common arbovirus in the world. In Africa, dengue virus is endemic in almost every country; however, in Togo few data are available. The aim of this study was to estimate the prevalence of dengue fever among patients with febrile syndrome at the Centre hospitalier universitaire Sylvanus Olympio of Lomé. A cross sectional study was conducted in the Centre hospitalier universitaire Sylvanus Olympio of Lomé.

Results: One hundred forty-seven patients with a median age of 36 years, interquartile range: [23.5-51.5], were included in the study. The prevalence of malaria in the sample was 10.2% (95% CI: [5.8-16.3]) and the prevalence of dengue fever by ELISA was 17% (95% CI: [11.3-24.1]). The overall percent agreement between the RDT Dengue NS1 and ELISA for dengue was 80.9% (95% CI: [73.7-86.9]). The positive percent agreement (PPA) between the RDT assay and the ELISA assay considered as the reference was 36%, 95% CI: [17.9-57.5]), while the negative percent agreement (NPA) between the two assays was 90.2% (95% CI: [83.4-94.8]).

Conclusion: This study shows that dengue is as much as malaria responsible of febrile syndromes and that it is present in Togo.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128494PMC
http://dx.doi.org/10.48327/mtsi.2021.183DOI Listing

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