The Casein Kinase II is associated with meiotic DNA in fertilized oocytes.

MicroPubl Biol

Department of Biological Sciences, Oakland University, Rochester, MI, USA.

Published: June 2022

By using CRISPR/Cas9 genome-editing, we have generated epitope-tagged KIN-3 and KIN-10 expressing strains at the endogenous C-terminal loci in . We observed that both the catalytic (KIN-3::V5) and regulatory (KIN-10::2xMyc) subunits of the Casein Kinase II (CK2) holoenzyme complex are associated with meiotic DNA, enriched in the midvalent rings during meiotic divisions in fertilized oocytes.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171554PMC
http://dx.doi.org/10.17912/micropub.biology.000583DOI Listing

Publication Analysis

Top Keywords

casein kinase
8
associated meiotic
8
meiotic dna
8
fertilized oocytes
8
kinase associated
4
dna fertilized
4
oocytes crispr/cas9
4
crispr/cas9 genome-editing
4
genome-editing generated
4
generated epitope-tagged
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!