Accurately predict the efficiency of centrifugal pumps at different rotational speeds is important but still intractable in practice. To enhance the prediction performance, this work proposes a hybrid modeling method by combining both the process data and knowledge of centrifugal pumps. First, according to the process knowledge of centrifugal pumps, the efficiency curve is divided into two stages. Then, the affinity law of pumps and a Gaussian process regression (GPR) model are explored and utilized to predict the efficiency at their suitable flow stages, respectively. Furthermore, a probability index is established through the prediction variance of a GPR model and Bayesian inference to select a suitable training set to improve the prediction accuracy. Experimental results show the superiority of the hybrid modeling method, compared with only using mechanism or data-driven models.
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http://dx.doi.org/10.3390/s22114300 | DOI Listing |
Annu Int Conf IEEE Eng Med Biol Soc
July 2024
Mechanical circulatory support (MCS) devices play a quintessential role in providing hemodynamic support to heart failure patients. The development of short-term compact percutaneous MCS devices which are ideal for emergency acute heart failure applications is one of the promising advances in MCS technologies. This study presents the design and preliminary performance evaluation of a compact percutaneous centrifugal blood pump which is potentially ideal for the quick provision of left ventricular support during emergency cardiac arrest.
View Article and Find Full Text PDFSheng Wu Yi Xue Gong Cheng Xue Za Zhi
December 2024
Shanghai Key Laboratory of Multiphase Flow and Heat Transfer in Power Engineering, School of Energy and Power Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P. R. China.
The impeller, as a key component of artificial heart pumps, experiences high shear stress due to its rapid rotation, which may lead to hemolysis. To enhance the hemolytic performance of artificial heart pumps and identify the optimal combination of blade parameters, an optimization design for existing pump blades is conducted. The number of blades, outlet angle, and blade thickness were selected as design variables, with the maximum shear stress within the pump serving as the optimization objective.
View Article and Find Full Text PDFPerfusion
February 2025
Division of Pediatric Surgery, Department of Surgery, Columbia University Vagelos College of Physicians and Surgeons/NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, NY, USA.
Introduction: Extracorporeal membrane oxygenation (ECMO) is utilized in critically ill neonates with severe cardiopulmonary failure. Hemolysis is a potential complication and is associated with significantly increased morbidity and mortality. The etiology of hemolysis in neonates is multifactorial, including shear forces generated by the ECMO pump, higher flow resistance from smaller tubing and smaller cannulas, the oxygenator, and other patient factors.
View Article and Find Full Text PDFHeliyon
January 2025
Convergence Manufacturing System Engineering (Green Process and Energy System Engineering), University of Science & Technology, Daejeon, 34113, South Korea.
Single-channel pump is a type of centrifugal pump that is frequently utilized for wastewater treatment around the world, but they often operate at low flow rates with low efficiency and loud noise because the wastewater contains many impurities. In this study, an adjustable tongue vane was developed that controls the internal flow direction in the volute to increase the energy performance of a single-channel pump. Numerical simulations were conducted by using Reynolds-averaged Navier-Stokes equations and shear stress transport turbulence model to evaluate the energy loss inside the volute.
View Article and Find Full Text PDFBiofabrication
February 2025
Department of Chemical Engineering, Feng Chia University, No. 100, Wenhua Road, Taichung 407102, Taiwan.
Drug screening is an indispensable procedure in drug development and pharmaceutical research. For cell-based drug testing, cells were treated with compounds at different concentrations, and their responses were measured to assess the compounds' effects on cellular behavior. A concentration gradient test creates a growth environment with different compound concentrations for cultured cells, facilitating faster determination of the compound concentration's effect on cellular responses.
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