AI Article Synopsis
- * These compounds were isolated from the organic extract of an endozoic fungus sourced from a deep-sea coral collected at a depth of 1458 meters in the Magellan Seamount.
- * Their structures were analyzed using NMR, mass spectrometry, NOESY correlations, X-ray diffraction, and ECD calculations, and all compounds were tested for antimicrobial properties against various pathogenic bacteria and fungi.
Article Abstract
Four unusual steckwaic acids E-H (-), possessing a rarely described acrylic acid unit at C-4 (-) or a double bond between C-12 and C-13 () are reported for the first time, along with four new analogues (-) and two known congeners ( and ). They were purified from the organic extract of AS-324, an endozoic fungus obtained from a deep-sea coral sp., which was collected from the Magellan Seamount at a depth of 1458 m. Their structures were determined by the interpretation of NMR and mass spectroscopic data. The relative and absolute configurations were determined by NOESY correlations, X-ray crystallographic analysis, and ECD calculations. All compounds were tested for their antimicrobial activities against human- and aquatic-pathogenic bacteria and plant-related pathogenic fungi.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181172 | PMC |
| http://dx.doi.org/10.3390/ijms23116332 | DOI Listing |
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