AI Article Synopsis
- The study investigates the cancer burden of lip and oral cavity, nasopharyngeal, and other pharyngeal cancers (LOCP) in Europe using 2019 Global Burden of Disease data.
- Lip and oral cavity cancer has seen a decrease in incidence, while nasopharyngeal and other pharyngeal cancers experienced increases from 1990 to 2019, with significant variations across different European regions.
- Eastern Europe, especially Hungary, faces the highest burden of LOCP, and specific trends show differing impacts of tobacco on cancer incidence and disability-adjusted life years (DALYs) in Ireland compared to the EU average.
Article Abstract
-The recent burden of lip and oral cavity, nasopharynx and other pharynx cancer (LOCP) has not been specifically investigated in Europe. -In this descriptive epidemiological study, LOCP was categorised into lip and oral cavity cancer, nasopharynx cancer and other pharynx cancer, with European trends documented using the 2019 Global Burden of Disease (GBD). Summary statistics included deaths, age-standardised incidence rates (ASIR), mortality rates, YLLs (years of life lost), YLDs (years of life lived with disability) and DALYS (disability-adjusted life years). -Lip and oral cavity cancer (LO) is the most dominant with the incidence decreasing from 6.2 new cases per 100,000 (95% UI: 6.1-6.4) in 1990 to 5.3 new cases per 100,000 (95% UI: 4.6-6.1). However, nasopharynx cancer (NP) and other pharynx cancer (OP) increased from 1 and 2.2 new cases per 100,000 in 1990 to 1.1 and 3.3 new cases per 100,000 in 2019, respectively. It was noted that LOCP YLLs is much higher than YLDs. In Europe, eastern European countries, specifically Hungary, have the highest burden of LOCP. When LOCP attributable to tobacco in Ireland was compared with the EU, the percentage decrease in OP DALYs attributable to tobacco is below the EU average, whereas the percentage decrease in LO attributable to tobacco in Ireland was above the EU average. -There has been a significant increase in ASIR in categories other pharynx and nasopharynx cancer since 1990, with significant geographic variations.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180496 | PMC |
| http://dx.doi.org/10.3390/ijerph19116532 | DOI Listing |
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