AI Article Synopsis

  • Lower hand grip strength is linked to cognitive impairment in older Chinese adults, with a study examining 6806 participants aged 50 and above.
  • The research found that both absolute and relative grip strength were significantly associated with recall memory performance, as measured by the Delayed Word Recall Test (DWRT), but not with overall cognitive function (MMSE scores).
  • These findings suggest a specific relationship between grip strength and memory recall, indicating the need for further research in this area.

Article Abstract

Background: Lower hand grip strength has been linked to cognitive impairment, but studies in older Chinese are limited. We examined the association of hand grip strength with cognitive function in a large sample of older Chinese. Methods: 6806 participants aged 50+ years from the Guangzhou Biobank Cohort Study (GBCS) were included. Relative grip strength was calculated by absolute handgrip strength divided by the body mass index (BMI). Cognitive function was assessed using the Delayed Word Recall Test (DWRT, from 0 to 10) and the Mini Mental State Examination (MMSE, from 0 to 30), with higher scores indicating better cognition. Results: After adjusting for multiple potential confounders, lower absolute grip strength and relative grip strength were significantly associated with lower DWRT (all p < 0.05) in all participants. No significant interaction effects between sex and handgrip strength on cognitive impairment were found (p from 0.27 to 0.87). No significant association between handgrip strength and total MMSE scores was found in the total sample or by sex (p from 0.06 to 0.50). Regarding the individual components of MMSE, lower absolute and relative grip strength were significantly associated with lower scores of the recall memory performance in all participants (p from 0.003 to 0.04). Conclusion: We have shown for the first time a positive association of grip strength with recall memory performance, but not general cognitive function in older people, which warrants further investigation.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180839PMC
http://dx.doi.org/10.3390/ijerph19116464DOI Listing

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