AI Article Synopsis

  • The study analyzed 298 Mongolian patients with cerebral infarction to determine age distribution and the relationship between thromboelastography (TEG) and standard coagulation measures.
  • Most patients were aged 61-70, indicating a younger trend in onset age, with significant correlations found between TEG results and certain coagulation parameters.
  • While there is a correlation between TEG and coagulation measurements, the consistency between the two methods is weak, meaning they cannot substitute for one another in clinical practice.

Article Abstract

Objective: To investigate the age distribution of Mongolian patients with cerebral infarction caused by thrombosis and the correlation and consistency between thromboelastography (TEG) and four parameters of coagulation.

Methods: The age distribution of 298 Mongolian patients with cerebral infarction treated in Affiliated Hospital of Inner Mongolia Minzu University from January 2020 to December 2021 and their TEG, four items of routin coagulation and platelet count were analyzed retrospectively. The correlation and consistency of above-mentioned two detection methods were statistically analyzed.

Results: The onset age of 298 Mongolian patients with cerebral infarction was mainly 61-70 years old, accounting for 38.3%, followed by 51-60 years old, accounting for 26.8%. The R time detected by TEG was linearly correlated with PT and APTT(r=0.186,r=0.152). K value, MA value and α-Angle measured by TEG was linearly correlated with Fib (r=-0.364,r=0.616,r=0.359), K value, MA value and α-Angle measured by TEG was linearly correlated with Plt (r=0.318,r=0.519,r=0.301). The R time detected by TEG was consistent with PT and APTT, and the Kappa values were 0.252 (P<0.001), 0.336 (P<0.001). K, MA, and α-Angle measured by TEG was consistent with Fib, the Kappa values were 0.265 (P<0.001), 0.289 (P<0.001) and 0.290 (P<0.001), respectively; K、MA and α-Angle measured by TEG was consistent with Plt, the Kappa values were 0.276 (P<0.001), 0.285 (P<0.001) and 0.302 (P<0.001), respectively.

Conclusion: The onset age of Mongolian patients with cerebral infarction caused by thrombosis is mainly 61-70 years old, followed by 51-60 years old. The onset age shows a younger trend. There is a significant correlation between TEG and coagulation, but the consistency is weak, therefore, the two methods can not be replaced each other.

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http://dx.doi.org/10.19746/j.cnki.issn.1009-2137.2022.03.031DOI Listing

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