Here we describe and illustrate the sites of venipuncture in the alligator using CT reconstructions, cross-sectional anatomy, and traditional dissection. We also describe the clinical approach for each venipuncture site and describe a novel site for venipuncture in crocodilians, the lateral occipital sinus. Based on the authors' experience, the lateral occipital sinuses offer the safest, simplest, and most consistent access for venipuncture in the alligator. Future studies should examine other crocodilian species to confirm the presence of the lateral occipital sinuses.
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http://dx.doi.org/10.1002/ar.24995 | DOI Listing |
Alzheimers Dement
December 2024
Universitary Hospital M Valdecilla, Santander, Cantabria, Spain.
Background: Preclinical Alzheimer's disease may be linked to impaired cerebral amyloid clearance. We aim to obtain dynamic parameters of cortical and ventricular clearance of C-PIB and compare them with CSF amyloid values in a population of healthy volunteers.
Method: We evaluated 8 healthy volunteers (4 men and mean age: 64.
Alzheimers Dement
December 2024
Illinois Institute of Technology, Chicago, IL, USA.
Background: Brain arteriolosclerosis is characterized by the thickening of vessel walls and arteriolar stenosis and is one of the primary pathologies of cerebral small vessel disease. Arteriolosclerosis is linked to lower cognitive and motor function, as well as an elevated risk of dementia. This study aimed to investigate the association of brain arteriolosclerosis with regional gray matter volumes in a large number of community-based older adults.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Yale School of Medicine, New Haven, CT, USA.
Background: Affective cognition and emotion processing is impaired in amnestic Alzheimer's disease (AD), although less is known about atypical (AT) variants such as logopenic variant primary progressive aphasia (lvPPA) and posterior cortical atrophy (PCA). The affective blindsight pathway bypasses V1 via the superior colliculus-pulvinar route to activate the amygdala in cases of occipital lesioning and may explain maintenance of emotion identification and visual information processing in non-amnestic AD despite atrophy in visuospatial regions. We sought to characterize functional connectivity from key regions along the affective blindsight pathway in a clinically heterogeneous AD cohort.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of California, Davis, Davis, CA, USA.
Background: Depressive symptoms are associated with reduced brain integrity. However, it is unclear if this association holds among a racially and ethnically diverse population aged ≥90 years and if there are differences by gender.
Method: The LifeAfter90 Study enrolled 212 long-term members of Kaiser Permanente Northern California who were ≥90 years old, without dementia diagnosis, and received neuroimaging via 3T MRI.
Ann Biomed Eng
December 2024
Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, 1 Brookings Drive, MSC 1185-208-125, St. Louis, MO, 63130, USA.
Purpose: To determine how the biomechanical vulnerability of the human brain is affected by features of individual anatomy and loading.
Methods: To identify the features that contribute most to brain vulnerability, we imparted mild harmonic acceleration to the head and measured the resulting brain motion and deformation using magnetic resonance elastography (MRE). Oscillatory motion was imparted to the heads of adult participants using a lateral actuator (n = 24) or occipital actuator (n = 24) at 20 Hz, 30 Hz, and 50 Hz.
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