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Measurement Equivalence of Standard and Zoom-Enabled Electronic Clinical Outcome Assessments: Implications for Patient Accessibility in Clinical Trials.
Value Health
October 2024
Safira Clinical Research Ltd, Cloughjordan, Ireland; Insight SFI Research Centre for Data Analytics, Dublin City University, Dublin, Ireland.
Objectives: Diversity and inclusion in clinical trials remains an important topic, particularly for participants with disabilities such as vision impairment. With advances in smartphone and tablet technologies and their increasing use in clinical trials, accessibility features, such as pinch to zoom, are now at our fingertips. However, implementing such accessibility features when collecting electronic clinical outcomes assessments (eCOA) does not come without risks and must be designed with careful consideration and scientifically tested to ensure no impact to data integrity.
View Article and Find Full Text PDFThe Differences in Content of Health Care Plans of Medical and Nursing Students in Interprofessional and Uniprofessional Education.
J Med Educ Curric Dev
September 2024
Teaching & Learning Centre (TLC) FdG - UvA, Amsterdam UMC location AMC, Amsterdam, the Netherlands.
Background: With a growing population of older people in all Western countries, interprofessional education (IPE) can help to prepare students for the complex care for these patients. Which aspects of this complex care could benefit from IPE? In this study we evaluated the differences in content of health care plans made by students who participated in IPE.
Methods: Undergraduate nursing and medical students were included and attended four sessions in which they wrote a health care plan for a paper-based geriatric patient case.
Zooming into the Complex Dynamics of Electrodermal Activity Recorded during Emotional Stimuli: A Multiscale Approach.
Bioengineering (Basel)
May 2024
Dipartimento di Ingegneria dell'Informazione, University of Pisa, 56122 Pisa, Italy.
Physiological phenomena exhibit complex behaviours arising at multiple time scales. To investigate them, techniques derived from chaos theory were applied to physiological signals, providing promising results in distinguishing between healthy and pathological states. Fractal-like properties of electrodermal activity (EDA), a well-validated tool for monitoring the autonomic nervous system state, have been reported in previous literature.
View Article and Find Full Text PDFTherapeutic biomarkers in metastatic castration-resistant prostate cancer: does the state matter?
Crit Rev Clin Lab Sci
May 2024
Department of Experimental Urology, Research Institute of Medical Innovation, Radboud university medical center, Nijmegen, The Netherlands.
Article Synopsis
- The treatment of metastatic castration-resistant prostate cancer (mCRPC) is advancing due to improved understanding of its biology and the use of precision oncology, which matches therapies to specific tumor genotypes.
- Obtaining and sequencing tumor DNA, especially through circulating tumor DNA (ctDNA), is crucial for tracking real-time genetic changes, treatment response, and tumor heterogeneity, making ctDNA a potential prognostic biomarker.
- Recent developments include third-generation androgen receptor inhibitors to address resistance mechanisms and PARP inhibitors targeting DNA damage repair defects, providing new options for patients with specific genetic mutations.
Small Zoom Mismatch Adjustment Method for Dual-Band Fusion Imaging System Based on Edge-Gradient Normalized Mutual Information.
Sensors (Basel)
April 2023
MOE Key Laboratory of Optoelectronic Imaging Technology and System, Beijing Institute of Technology, Beijing 100081, China.
Currently, automatic optical zoom setups are being extensively explored for their applications in search, detection, recognition, and tracking. In visible and infrared fusion imaging systems with continuous zoom, dual-channel multi-sensor field-of-view matching control in the process of synchronous continuous zoom can be achieved by pre-calibration. However, mechanical and transmission errors of the zoom mechanism produce a small mismatch in the field of view after co-zooming, degrading the sharpness of the fusion image.
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