Chronic Low-Level Cyanide Intoxication in an Electroplating Plant in Taiwan.

J Occup Environ Med

From the Department of Occupational Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan (Dr Fan, Dr Luo, Dr Tsao); College of Medicine, Chang Gung University, Taoyuan, Taiwan (Dr Fan, Dr Yeh, Dr Tsao); New Taipei Municipal TuCheng Hospital, Chang Gung Memorial Hospital, Taoyuan, Taiwan (Dr Luo); Department of Family Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan (Dr Yeh); and Department of Occupational Medicine, Wan Fang Hospital, Taipei Medical University, Taipei City, Taiwan (Dr Huang).

Published: September 2022

AI Article Synopsis

  • The study focused on evaluating clinical symptoms in electroplating workers exposed to cyanide, comparing responses from silver-plating and gold-plating workers.
  • Results indicated that silver-plating workers experienced higher levels of cyanide exposure and reported more health symptoms, such as nasal bleeding and skin scalding.
  • Urinary thiocyanates emerged as a potential biomarker for measuring cyanide exposure, linked to the level of exposure at the workers' respective plants.

Article Abstract

Objective: This study aimed to investigate clinical symptoms among electroplating workers exposed to cyanide.

Methods: In this study, 26 silver-plating and 51 gold-plating workers completed questionnaires and were tested for urinary thiocyanates. Air cyanide, urinary thiocyanates, and clinical symptoms were compared between workers using Student t and χ 2 test and further analyzed by multivariate linear regression.

Results: Air cyanide and urinary thiocyanate were higher in the silver-plating plant than the gold-plating plant. In both plants, a dose-response relationship was observed between exposure status and thiocyanate levels. Silver-plating workers reported a higher frequency of almond odor detection, nasal bleeding, excessive salivation, skin scalding, and corrosion. Urinary thiocyanates were associated with the plant and exposure status, but not with smoking.

Conclusions: Our study suggests that silver-plating workers had higher exposure and more symptoms. Urinary thiocyanate may be a useful biomarker for cyanide exposure.

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Source
http://dx.doi.org/10.1097/JOM.0000000000002584DOI Listing

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