AI Article Synopsis
- Every healthcare interaction with children is a chance to deliver both immediate care and ongoing health support.
- A Clinical Decision Support (CDS) system was launched in a specialized pediatric hospital to boost influenza vaccination rates among eligible children during the 2019-2020 flu season.
- The study investigates the reasons behind the low vaccine uptake despite the CDS implementation and seeks potential solutions to enhance flu vaccine coverage.
Article Abstract
Every heatlhcare encounter is an opportunity to provide both acute care and health maintenance to children. A Clinical Decision Support (CDS) intervention was instituted in a tertiary pediatric health system to improve influenza vaccination rates during the 2019-2020 season among eligible children receiving care in an acute care inpatient healthcare setting. This study explores reasons for low vaccine uptake following implementation of a CDS aimed at improving vaccine administration as well as identifying possible solutions to improve flu vaccine coverage.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3233/SHTI220116 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Medical mistrust and COVID-19 vaccine attitudes and behavior: Findings from a population-based cohort study in Michigan.
Vaccine X
January 2025
Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, United States.
Background: Uptake of COVID-19 vaccines has stalled in the U.S. Some studies suggest that medical mistrust may be a barrier, but evidence is limited due to cross-sectional designs or convenience sampling.
View Article and Find Full Text PDFExploring perceptions and attitudes towards vaccines in a remote western DRC health zone.
Vaccine X
January 2025
Global Health Institute, Department of Family Medicine and Population Health, University of Antwerp, Antwerp, Belgium.
The Democratic Republic of the Congo (DRC) struggles with low full childhood vaccination coverage (around 50 %) and a high children-under-five mortality rate (79 deaths per 1000 live births). This situation is potentially exacerbated by vaccine hesitancy, which was identified by the World Health Organization (WHO) as one of the top 10 global health threats in 2019. To gain deeper insights into levels of vaccine confidence possibly influencing vaccination coverage, we explored perceptions and attitudes towards childhood and adult vaccines in Boende (Tshuapa province, western DRC), which experienced an Ebola outbreak in 2014 and hosted the EBL2007 Ebola vaccine trial (2019-2022).
View Article and Find Full Text PDFEvaluation of parent reminder-recall letters to promote human papillomavirus vaccination.
Prev Med Rep
January 2025
Department of Quantitative Health Sciences, Mayo Clinic, Rochester, 200 First Street SW, Rochester, MN 55905, USA.
Objective: Human papillomavirus (HPV) vaccine uptake remains suboptimal. Our stepped-wedge cluster randomized trial found that reminder-recall letters sent to parents of age-eligible children significantly increased vaccine uptake compared to usual care. Subsequently, we conducted a process evaluation to assess the mechanisms of the letter's effectiveness.
View Article and Find Full Text PDFPatterned Antigens on DNA Origami Controls the Structure and Cellular Uptake of Immune Complexes.
ACS Nano
January 2025
Institute of Biomedical Engineering, University of Toronto, Toronto M5S 2E3, Canada.
Immune complexes (ICs), formed via antibody (Ab)-antigen (Ag) binding, trigger diverse immune responses, which are critical for natural immunity and have uses for vaccines and immunotherapies. While IC-elicited immune responses depend on its structure, existing methods for IC synthesis produce heterogeneous assemblies, which limits control over their cellular interactions and pharmacokinetics. In this study, we demonstrate the use of DNA origami to create synthetic ICs with defined shape, size, and solubility by displaying Ags in prescribed spatial patterns.
View Article and Find Full Text PDFA respiratory mucosal vaccine based on chitosan/aluminum adjuvant induces both mucosal and systemic immune responses.
Int J Pharm
January 2025
State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health (School of Life Science), Xiamen University, Xiamen, Fujian 351002, China; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, National Innovation Platform for Industry-Education Integration in Vaccine Research, NMPA Key Laboratory for Research and Evaluation of Infectious Disease Diagnostic Technology, Xiamen University, Xiamen, Fujian 361102, China. Electronic address:
The respiratory mucosa serves as a critical barrier against the invasion of pathogens. Effective mucosal vaccines are essential for enhancing local immunity. However, there is an urgent need to develop new mucosal adjuvants.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!