The present research letter reports the 1-year clinical outcomes of the randomized COMPARE CRUSH trial, which allocated STEMI patients at first medical contact in the ambulance to receive either crushed or integral tablets of prasugrel loading dose. This trial aimed to investigate whether early enhanced antiplatelet effect constituted by the crushed potent oral P2Y inhibitor prasugrel could lead to improved early myocardial reperfusion and clinical outcomes.

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http://dx.doi.org/10.1016/j.ahj.2022.05.022DOI Listing

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