Copper-catalyzed C2 alkenylation of pyridine--oxides with alkynes.

Chem Commun (Camb)

School of Environmental and Chemical Engineering, Jiangsu Ocean University, Lianyungang 222005, China.

Published: June 2022

A general and expedient method to construct the scaffolds of 2-alkenylpyridines, through copper-catalyzed C2 alkenylation of pyridine--oxides with alkynes, has been disclosed. This protocol shows operational simplicity, good functional group compatibility and broad substrate scope.

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Source
http://dx.doi.org/10.1039/d2cc00851cDOI Listing

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