Affect theory raises greater awareness of non-representational forces in social life that can shape different levels of subjectivity in ways that may not be immediately known to the subjects. In outbreaks of mass hysteria when subjects are suddenly exposed to bizarre and extreme behaviors, the question of affect becomes a key to understanding how their subjectivity is impacted by situations that seemingly slip immediate control. Hysterical subjectivity occurs not from unconscious forces but from affective contagions spreading throughout network assemblages. These are flows of fear and conflict that with non-conscious influences constitute the new forces of mass encounters. In these encounters, micro-flows of imitation are automatized by various assemblages of intention and action to produce repeatable contagions of affects and behaviors. The occurrence of the COVID-19 pandemic demonstrates the power of these flows as facilitating a global affectivity of mass hysteria. It is an affectivity in which imitation takes on a central role as technology of the social for the behavioral control of mass populations. Ubiquitous mask-wearing in the pandemic is not only seen as a prophylactic against viral infection but also intended as a mandated form of mimicry for propagating the new politics of virality. These are politics that empower fear as an agent of cascading contagions paralyzing social, cultural, and economic life around the world.
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http://dx.doi.org/10.1057/s41286-022-00127-6 | DOI Listing |
BMC Med Genomics
January 2025
Center for Medical Genomics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
Background: Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency (21-OHD CAH) is an autosomal recessive disorder resulting from pathogenic variants in the CYP21A2 gene. The disorder exhibits variable clinical severity, with the classical form manifesting as salt-wasting crisis in neonates, while inducing ambiguous genitalia in females and precocious puberty in males through simple virilization. Identifying at-risk couples during the preconception stage holds significance for optimizing reproductive choices.
View Article and Find Full Text PDFGenes (Basel)
November 2024
Clinic for Small Animal Internal Medicine, Vetsuisse Faculty University of Zürich, 8057 Zürich, Switzerland.
In heme degradation, biliverdin reductase catalyzes the conversion of biliverdin to bilirubin. Defects in the biliverdin reductase A gene () causing biliverdinuria are extraordinarily rare in humans, and this inborn error of metabolism has not been reported in other mammals. The objective of this study was to diagnose biliverdinuria and identify the causal variants in two adult mixed-breed dogs with life-long green urine.
View Article and Find Full Text PDFArch Womens Ment Health
November 2024
Neuroendocrine Unit, Massachusetts General Hospital, 50 Staniford St., Suite 750B, Boston, MA, 02114, USA.
J Clin Tuberc Other Mycobact Dis
December 2024
Rīga Stradiņš University, Riga, Latvia.
Background: The recurrence of tuberculosis (TB) continues to place a significant burden on patients and TB programs worldwide. Repeated TB episodes can develop either due to endogenous reactivation of previously treated TB or exogenous reinfection with a distinct strain of (Mtb). Determining the precise cause of the recurrent TB episodes and identifying reasons for endogenous reactivation of previously successfully treated patients is crucial for introducing effective TB control measures.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Basis Dis
January 2025
Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan 430022, China; Hubei Key Laboratory of Metabolic Abnormalities and Vascular Aging, 1277 Jiefang Avenue, Wuhan 430022, China; Hubei Clinical Research Center of Metabolic and Cardiovascular Diseases, 1277 Jiefang Avenue, Wuhan 430022, China. Electronic address:
Background & Aims: Gut inflammation caused by diets could damage the intestinal barrier, which increases the liver exposition to pathogenic substances. Toll-IL-1 receptor (TIR) domain-containing adaptor molecule-1 (Ticam1) is a key molecule in the Toll-like receptors (TLRs) pathway, which is important for the immune defense against pathogens such as bacteria or viruses. In this study, mouse intestinal epithelial cell (IEC) Ticam1 was knocked out to suppress the intestinal inflammation response in metabolic dysfunction-associated steatohepatitis (MASH) to investigate its influence on the development of MASH.
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