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Monkeypox (mpox) is a rare viral disease that can cause severe illness in humans, with outbreaks occurring primarily in central and western Africa. Well-coordinated and synchronized efforts are necessary to understand the factors involved in disease transmission and develop effective health interventions. The aim of this study is to assess the relationship between climate factors and daily mpox cases, as well as to identify the most suitable predictive model for transmission.

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Mpox (formerly known as monkeypox), an infectious disease caused by the monkeypox virus (MPXV), has been endemic in regions of Central and Western Africa. In 2022, the global spread of the clade IIb MPXV led to a multinational outbreak, primarily affecting sexual transmission networks among men who have sex with men. Despite interventions, new cases have continued to emerge.

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Molecular Aspects of the Monkeypox Virus and their Impact on the Virus's Change in Epidemiology.

P R Health Sci J

September 2024

Pedro Ruiz Gallo National University, Faculty of Biological Sciences, Department of Microbiology, Inmunología y Virología del Norte's group, Lambayeque, Peru.

Article Synopsis
  • Monkeypox, a viral disease primarily found in West and Central Africa, has seen a significant increase in cases globally over the last decade, particularly during a multinational outbreak in 2022, suggesting possible evolutionary changes in the virus.
  • A review of 271 articles published during the outbreak period identified 49 relevant studies that highlight challenges related to waning immunity, altered transmission routes, and genomic changes in the virus, complicating containment efforts.
  • The findings suggest that Monkeypox may be filling an ecological niche previously occupied by smallpox, with specific genetic mutations being linked to its recent epidemiological changes and the need for continued surveillance and vaccination to control future outbreaks.
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Background: The COVID-19 pandemic and subsequent multinational mpox outbreak significantly disrupted sexual health care delivery, particularly impacting men who have sex with men (MSM). This study investigated these public health emergencies in relation to perceptions, attitudes, and sexual practices among MSM affiliated with a collective sex venue (CSV).

Methods: Electronic surveys were sent to clientele of a high-volume CSV between June 2021 and November 2022 across 3 time periods defined as pre-Omicron, post-Omicron, and mpox.

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We assessed early antibody responses after two doses of JYNNEOS (IMVANEX) mpox vaccine in the District of Columbia (D.C.) in persons at high risk for mpox without characteristic lesions or rash.

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