Self assembled three dimensional β-CuVO hierarchical flower decorated porous carbon: An efficient electrocatalyst for flutamide detection in biological and environmental samples.

The serious situation mandates the use of anticancer drugs, which protect people all over the world from the growth of prostate cancer. In particular, excessive dosage and erroneous discharge of flutamide concentration cause make environmental pollution on the surface of the wastewater. In this study, the highly sensitive and selective electrochemical approach based on copper vanadium oxide decorated porous carbon (denoted as β-CuVO/PC) composite modified glassy carbon electrode (GCE) has been developed and it was applied for sensitive detection of anticancer drug flutamide (FTM). Moreover, using the co-precipitation method, the flower-like β-CuVO hierarchical microstructure was synthesized, and through the wet chemical process, the β-CuVO/PC composite was obtained. The resultant product was characterized by XRD, FTIR, RAMAN, XPS and structural morphology established by FESEM analysis. Besides that, the electrochemical characterization and properties were analyzed by cyclic voltammetry (CV) and amperometric (i-t) techniques. The β-CuVO/PC/RDGCE had two linear ranges at 0.01-2.11 μM and 2.31-30.81 μM. The lower limits of detection and sensitivity were found at 0.62 nM (S/N = 3), and 24.33 μA μM cm respectively. The practicability test was applied for the determination of FTM in urine, blood serum and environmental aquatic fluid with satisfactory recovery obtained.