Aim: To study the role of check point inhibitors (CPI) in sarcoma and gastrointestinal stromal tumors.
Materials & Methods: Retrospective data of 15 patients diagnosed with advanced sarcoma or gastrointestinal stromal tumors and treated with CPI.
Results: 3/14 patients (21.4%) responded to treatment with a disease control rate of 42.8% (6/14). After a median follow-up of 14 months (range: 2-24 months), 11 (73.3%) patients progressed, the median progression-free survival was 4 months (95% CI: 1.7-6.3) and median overall survival was 14 months (95% CI: 2.6-25.7). Only one patient experienced a grade IV adverse event.
Conclusion: Our data represent the first real-world application of CPI in sarcoma from India. We believe that CPI should be further evaluated in clinical trials.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136636 | PMC |
| http://dx.doi.org/10.2144/fsoa-2021-0117 | DOI Listing |
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