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Inhibition of biofilm formation and preformed biofilm in by resveratrol, chlorhexidine and benzalkonium: modulation of efflux pump activity.
Front Microbiol
December 2024
Department of Public Health, University of Naples Federico II, Naples, Italy.
Introduction: The persistence of in the contaminated environment is sustained by tolerance to biocides and ability to growth as biofilm. The aim of the study was to analyze the susceptibility of biofilms to chlorhexidine (CHX) and benzalkonium (BZK) biocides and the ability of natural monomeric stilbenoid resveratrol (RV) to modulate the phenomenon.
Methods: Biofilm formation and preformed biofilm were tested by Crystal violet and tetrazolium salt reduction assay, respectively.
Hydrazidomethyl starch as a pH-sensitive coating for magnetic core in tailored magnetic nanoparticles with selective doxorubicin release.
Int J Biol Macromol
December 2024
Nicolaus Copernicus University in Torun, Faculty of Chemistry, Department of Biomedical Chemistry and Polymers, Medicinal Chemistry Research Group, Gagarina 7, 87-100 Torun, Poland. Electronic address:
The work aimed to use and modify starch as a biodegradable and biocompatible polysaccharide to create a modern pH-sensitive anticancer drug carrier based on a hydrazone bond. The multi-step reaction created a material that can bind to the carbonyl group of anticancer drugs. Additionally, polysaccharide was used to coat magnetic nanoparticles to increase the applicability of the carrier system.
View Article and Find Full Text PDFFunctionalization of silk with actinomycins from s BV365 for biomedical applications.
Front Bioeng Biotechnol
September 2024
Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
Silk, traditionally acclaimed as the "queen of fiber," has been widely used thanks to its brilliant performance such as gentleness, smoothness and comfortableness. Owing to its mechanical characteristics and biocompatibility silk has a definitive role in biomedical applications, both as fibroin and fabric. In this work, the simultaneous dyeing and functionalization of silk fabric with pigments from BV365 were investigated.
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J Labelled Comp Radiopharm
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PET Science Centre, Precision Medicine and Biosamples, Oncology R&D, AstraZeneca, Stockholm, Sweden.
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