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BCG-Induced DNA Methylation Changes Improve Coronavirus Disease 2019 Vaccine Immunity Without Decreasing the Risk for Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
Open Forum Infect Dis
January 2025
Global Tuberculosis Program, William T. Shearer Center for Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Background: The BCG vaccine induces trained immunity, an epigenetic-mediated increase in innate immune responsiveness. Therefore, this clinical trial evaluated if BCG-induced trained immunity could decrease coronavirus disease 2019 (COVID-19)-related frequency or severity.
Methods: A double-blind, placebo-controlled clinical trial of healthcare workers randomized participants to vaccination with BCG TICE or placebo (saline).
Peculiarities of in-Stent Thrombosis and Restenosis in Coronary Arteries Post-COVID-19: A Systematic Review of Clinical Cases and Case Series.
Open Access Emerg Med
January 2025
Nuclear Medicine Department, Center of Nuclear Medicine and Oncology, Semey, Abay Region, Kazakhstan.
Background: One of the most serious complications of coronary artery stenting is restenosis and in-stent thrombosis; their prevalence can reach 20-25%. Stent thrombosis can be acute (up to 24 hours), subacute (24 hours to 30 days), late (30 days to 1 year), and very late (> 1 year after previous stenting). In the patients with COVID-19 in intensive care units, the proportion of those with elevated troponin levels reached 25%.
View Article and Find Full Text PDFComparison of Bicortical versus Unicortical Medial Malleolus Fixation.
J Am Podiatr Med Assoc
January 2025
*Department of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.
Background: Ankle fractures continue to increase in incidence and severity in an older, more challenging geriatric population. Medial malleolus fixation with partially threaded cancellous 4.0-mm screws, a common fixation method, has been shown to fail due to pullout strength.
View Article and Find Full Text PDFDehydroxylated Polyvinyl Alcohol Separator Enables Fast Kinetics in Zinc-Metal Batteries.
Small
January 2025
Helmholtz Institute Ulm (HIU), Helmholtzstrasse 11, 89081, Ulm, Germany.
Separators are critical components of zinc-metal batteries (ZMBs). Despite their high ionic conductivity and excellent electrolyte retention, the widely used glass fiber (GF) membranes suffer from poor mechanical stability and cannot suppress dendrite growth, leading to rapid battery failure. Contrarily, polymer-based separators offer superior mechanical strength and facilitate more homogeneous zinc (Zn) deposition.
View Article and Find Full Text PDFLongitidunal changes in accommodation amplitude after strabismus surgery.
J AAPOS
January 2025
Department of Ophthalmology, Kayseri City Hospital, Kayseri, Turkey.
Purpose To investigate changes in accommodation amplitude (AA) after strabismus surgery. Methods The medical records of patients who underwent full-tendon tenotomy on at least one rectus muscle between January 2023 and July 2023 were reviewed retrospectively. AA was evaluated objectively and monocularly with the autorefractometry (Tonoref III, ARK-1a, NIDEK Co Ltd, Gamagori, Japan).
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