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Primary Cutaneous Neoplasm With Rhabdomyosarcomatous Differentiation and a Melanoma-Like Mutational Landscape.
J Cutan Pathol
March 2025
Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Malignant melanoma (MM) is notorious for its wide range of morphologic variability. Rarely, MM may lose all melanocytic markers and adopt the morphologic and immunophenotypic characteristics of a different neoplasm in a process known as trans-differentiation (TMM). Distinguishing TMM from primary cutaneous neoplasms may be challenging and is often dependent on the identification of an adjacent conventional melanoma.
View Article and Find Full Text PDFGiant Primary Cutaneous Nodular Melanoma of the Forehead: A Case Report.
Geriatrics (Basel)
December 2024
Medicine for Older People, University Hospital Southampton, Tremona Road, Southampton SO16 6YD, UK.
The incidence of melanoma is increasing globally. The estimated worldwide incidence is projected to increase from 324,635 cases in 2020 to 510,000 in 2040. In the UK, melanoma accounts for 4% of all new cases of cancer.
View Article and Find Full Text PDFHerpes simplex virus presenting as an oropharyngeal mass.
Laryngoscope Investig Otolaryngol
December 2024
Department of Surgery, Otolaryngology/Head and Neck Surgery Section Virginia Tech Carilion School of Medicine Roanoke Virginia USA.
Objectives: Present a clinically challenging case of an immunocompetent 74-year-old male who presented with marked dyspnea and hemoptysis. After the airway was secured, direct laryngoscopy revealed a large, fungating, hemorrhagic mass of the left lateral pharyngeal wall and surrounding structures.
Methods: Chart review of a single patient.
Fungating mass on the breast of a male patient.
Dermatol Online J
October 2024
Department of Dermatology, Mayo Clinic, Jacksonville, Florida, USA.
Breast cancer is one of the most common malignancies that can lead to cutaneous metastasis. Dermatopathologists often play an important role in the diagnosis of breast cancer metastasis to the skin. Rarely, dermatopathologists render a histopathologic diagnosis of primary breast cancer.
View Article and Find Full Text PDFThoracic combined spinal epidural anaesthesia for exploratory laparoscopy and laparotomy (sigmoidectomy, colostomy): The first case in Palestine for the ASA5 patient.
SAGE Open Med Case Rep
December 2024
Deparment of Anesthesia, Al-Ahli Hospital, Hebron, Palestine.
Thoracic combined spinal epidural anaesthesia offers the ideal perioperative anaesthesia and analgesia. A 78-year-old female presented to our hospital with a hypertensive emergency, non-ST elevation myocardial infarction and pulmonary effusion. Then the patient had abdominal pain, constipation and vomiting.
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