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Determining the effective dose of esketamine combined with propofol for painless hysteroscopy: a prospective dose-finding study.
Front Pharmacol
December 2024
Department of Anesthesiology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Background: The combination of esketamine and propofol has become a common choice for total intravenous anesthesia in hysteroscopic procedures. However, the optimal effective dose has not yet been determined. The aim of this study was to determine the median effective dose (ED) and 95% effective dose (ED) of esketamine compounded with propofol for painless hysteroscopy.
View Article and Find Full Text PDFIncreasing Premedication for Neonatal Intubation: A Quality Improvement Initiative.
Pediatr Qual Saf
December 2024
Division of Neonatology, Department of Pediatrics, Hackensack-Meridian Health, Hackensack University Medical Center, Hackensack, N.J.
Introduction: Endotracheal intubation is frequent in the neonatal intensive care unit (NICU) but may result in neonatal distress and instability. Premedication reduces adverse effects, such as hypoxia, bradycardia, and pain. The Specific, Measurable, Achievable, Relevant and Time-Bound aim for this project was to increase premedication use for nonemergent neonatal intubation in a specific NICU from 22% to 80% from March 2021 to May 2023.
View Article and Find Full Text PDFEffects of Transcutaneous Electrical Acupoint Stimulation on the Incidence of Hypoxia in Elderly Patients Undergoing Painless Gastrointestinal Endoscopy: A Randomized Controlled Trial.
Pain Res Manag
December 2024
Department of Anesthesiology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.
Hypoxia is not uncommon in elderly patients during painless gastrointestinal endoscopy. This study aimed to determine the effectiveness of transcutaneous electrical acupoint stimulation (TEAS) in reducing the occurrence of hypoxia symptoms in elderly patients. Patients were randomly and equally grouped into sham control ( = 109) or TEAS group ( = 109) by using the random number table method.
View Article and Find Full Text PDFThe nociceptive withdrawal reflex during spinal analgesia in pigs undergoing veno-arterial extracorporeal membrane oxygenation: a prospective observational study.
Front Vet Sci
December 2024
Experimental Surgery Facility, Experimental Animal Center, Faculty of Medicine, University of Bern, Bern, Switzerland.
Introduction: Use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is still in the focus of research, in which pigs are commonly involved. During VA-ECMO, cardiovascular parameters are artificially manipulated and therefore not reliable indicators of nociception. Nociceptive withdrawal reflex (NWR) thresholds can be a suitable alternative in such a context.
View Article and Find Full Text PDFEffect of mild sedation and analgesia on radial artery cannulation in novice residents: a prospective, randomized controlled trial.
BMC Med Educ
December 2024
Department of Anesthesiology and Pain Medicine, the Affiliated Hospital of Jiaxing University, No.1882, South of the Second Ring Road, Jiaxing City, Zhejiang Province, 314000, China.
Background: Radial artery cannulation can be challenging, particularly for inexperienced providers. This study aimed to compare the success rates of resident physicians performing radial artery cannulation with mild sedation and analgesia versus without.
Materials And Methods: This study was a prospective, single-center, double-blind randomized controlled trial.
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