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Reconstruction Using a Bilobed Flap in a Patient With Recurrent Neck Soft Tissue Metastasis From Oral Cancer: A Case Report.
Ear Nose Throat J
December 2024
Department of Otolaryngology Head and Neck Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Soft tissue defects in the head and neck are frequently encountered, often resulting from trauma or the surgical management of malignancies. Flap reconstruction plays a critical role in the closure of these defects, aiming to minimize complications and improve cosmetic outcomes. While various flap techniques are commonly utilized in head and neck reconstruction, to the best of our knowledge, the bilobed flap has not been previously reported in this anatomical region.
View Article and Find Full Text PDFBilobed Gallbladder: A Rare Anatomical Variation Discovered During Laparoscopic Cholecystectomy.
Cureus
October 2024
Department of General Surgery, Mercy Fitzgerald Hospital, Darby, USA.
A bilobed gallbladder is a rare congenital anomaly with two lobes sharing a single cystic duct, typically diagnosed preoperatively and rarely identified intraoperatively. Only a small number of cases have been documented in medical literature with limited information on associated conditions. A 22-year-old male patient, with a past medical history of cholelithiasis and no prior surgical history, presented with acute right upper quadrant pain and was diagnosed with acute cholecystitis.
View Article and Find Full Text PDFArticle Synopsis
- GPRC6A is a G-protein coupled receptor that plays a role in regulating energy metabolism and sex hormone production, activated by various ligands like cations and testosterone.
- A structural model was created using Alphafold2 to identify key binding sites for ligands, including an orthosteric site and two allosteric modulator sites.
- Research shows that Ocn peptides function as positive allosteric modulators by binding to a unique site in GPRC6A's Venus fly trap domain, while certain mutations disrupt this activation, enhancing understanding of ligand-receptor interactions.
A "gullwing sign" on magnetic resonance imaging of extradural spinal tumors in dogs and cats allows prioritization of round cell neoplasia.
Vet Radiol Ultrasound
November 2024
Research Computing Support, Office of Innovative Technologies, University of Tennessee, Knoxville, Tennessee, USA.
Extradural neoplasms are the most common spinal tumors in small animals. A bilobed appearance of ventral extradural spinal lesions ("gullwing sign") on MRI has been described with various conditions. The objective of this retrospective study was to determine if a "gullwing sign" is more common with certain types of extradural tumors.
View Article and Find Full Text PDFThe Bilobed Flap - Critical Analysis and New Mathematically Precise Design.
Eplasty
July 2024
Department of Plastic Surgery, Apex Hospitals, Bikaner, Rajasthan, India.
Article Synopsis
- The bilobed flap is a key technique for reconstructing nasal defects, often modified to improve its effectiveness, but little attention has been paid to the importance of the pivot point in its design.
- Recent analysis reveals that the traditional Zitelli design has mathematical inaccuracies, prompting the proposal of a new design with a more precise pivot point placement 2.6 times the radius of the defect.
- Properly designing the bilobed flap as a rotation flap enhances its functionality, making it a more reliable option for nasal reconstruction.
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