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Prevalence and correlates of false-positive results after 3-D screening mammography among uninsured women in a community outreach program. | LitMetric

AI Article Synopsis

  • - The study investigates false-positive results in uninsured minority women undergoing 3-D mammography, analyzing data from 21,022 women in the Breast Screening and Patient Navigation (BSPAN) program in North Texas.
  • - False-positive rates were found to be 11.8% in women aged 40-49 and 9.6% in women aged 50-64, with increased odds related to certain demographic factors like hormone replacement therapy and prior mammograms.
  • - The findings highlight the need for further research to reduce false-positive rates and optimize resource use in community outreach programs aimed at this vulnerable population.

Article Abstract

False-positive results have been rarely investigated among uninsured minority women who undergo 3-D screening mammography. Here, we analyzed data from 21,022 women participating in the Breast Screening and Patient Navigation (BSPAN) program of North Texas with an aim to report prevalence and correlates of false-positive results after 3-D screening mammography, stratified by age. False-positives were defined as a negative diagnostic mammogram or a negative biopsy within 1 year of a positive screen. We used multivariable logistic regression to assess associations of demographic and clinical covariates and false positive results for age groups 40-49 and 50-64 years. Prevalence of false-positive results was 11.8% and 9.6% in the 40-49 and 50-64 age groups, respectively. Multivariable logistic regression demonstrated that, in the 40-49 age group, women who were non-menopausal, did not use hormone replacement therapy (HRT), and had self-reported prior mammograms had higher odds of false-positive results than those who were menopausal, used HRT and had no self-reported prior mammograms, respectively. In the 50-64 age group, women with a prior self-reported diagnostic mammogram had higher odds of false-positive results than those without a prior self-reported diagnostic mammogram. This study establishes contemporary evidence regarding prevalence and correlates of false-positive results after 3-D mammography in the unique BSPAN population, and demonstrate that use of 3-D mammography is not enough to reduce false-positive rates among uninsured women served through community outreach programs. Further research is needed to explore improved techniques to reduce false-positive rates, and ensure optimal use of scarce resources in outreach programs.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152806PMC
http://dx.doi.org/10.1016/j.pmedr.2022.101790DOI Listing

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