Device life time is a significant consideration in the cost of ownership of quantum cascade lasers (QCLs). The life time of QCLs beyond an initial burn-in period has been studied previously; however, little attention has been given to predicting premature device failure where the device fails within several hundred hours of operation. Here, we demonstrate how standard electrical and optical device measurements obtained during an accelerated burn-in process can be used in a simple support vector machine to predict premature failure with high confidence. For every QCL that fails, at least one of the measurements is classified as belonging to a device that will fail prematurely-as much as 200 h before the actual failure of the device. Furthermore, for devices that are operational at the end of the burn-in process, the algorithm correctly classifies all the measurements. This work will influence future device analysis and could lead to insights on the physical mechanisms of premature failure in QCLs.
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http://dx.doi.org/10.1038/s41598-022-13303-0 | DOI Listing |
J Control Release
January 2025
State Key Laboratory of Natural Medicines, Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, PR China; NMPA Key Laboratory for Research and Evaluation of Cosmetics, China Pharmaceutical University, Nanjing 211198, PR China. Electronic address:
The metastasis and recurrence of cancer post-surgery remain the major reasons for treatment failures. Herein, a photo-immune nanoparticle decorating with M1 macrophage membrane (BD@LM) is designed based on the inflammatory environment after surgical resection. By loading photosensitizer black phosphorus quantum dots (BPQDs) and chemotherapeutics doxorubicin (DOX) in BD@LM nanoparticles, an effective chemophototherapy-mediated immunogenic cell death of tumor cells is triggered, subsequently leading to the maturation of dendritic cells for further immune cascade.
View Article and Find Full Text PDFData Brief
February 2025
SCES, Strathmore University, Nairobi, Kenya.
Quantum Cascade Lasers (QCL) are promising semiconductor lasers, compact and powerful, but of complex design. Availability of structured data of the QCL properties can support data mining activities that seek to understand the relationship between these properties, for instance between the design and performance features. The main open source of QCL data is in scientific text which in most cases is usually unstructured.
View Article and Find Full Text PDFWe propose an alternative scheme for implementing the antibunching effects of two-magnon bundle in a hybrid ferromagnet-superconductor system, where a magnon mode from the yttrium iron garnet (YIG) sphere interacts with a three-level superconducting qubit via photon virtual excitation in the microwave cavity. With the help of the qubit driving from the ground state to the excited state, the cascaded emission of magnon occurs and then the two-magnon bundle is formed. By analyzing the ordinary and generalized second-order correlation functions, it is found that the antibunched two-magnon bundle could be achieved via properly choosing the system parameters, which is originated from the anharmonicity of dressed energy levels induced by magnon-qubit couplings.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Department of Biomaterials & Biomedical Technology (BBT), University Medical Centre Groningen (UMCG), Antonius Deusinglaan 1, Groningen, 9713 AV, The Netherlands.
Free radicals are believed to play a secondary role in the cell death cascade associated with various diseases. In Huntington's disease (HD), the aggregation of polyglutamine (PolyQ) not only contributes to the disease but also elevates free radical levels. However, measuring free radicals is difficult due to their short lifespan and limited diffusion range.
View Article and Find Full Text PDFChemSusChem
January 2025
Kwansei Gakuin University: Kansei Gakuin Daigaku, Department of Applied Chemistry for Environment, 1 Gakuen-Uegahara, 669-1330, Sanda, JAPAN.
The natural Z-scheme of oxygenic photosynthesis efficiently drives electron transfer from photosystem II (PSII) to photosystem I (PSI) via an electron transport chain, despite the lower energy levels of PSII. Inspired by this sophisticated mechanism, we present a layered cascade bio-solar cell (CBSC) that emulates the Z-scheme. In this design, chlorophyll derivatives (Chl) act as PSI analogs, while bacteriochlorophyll derivatives (BChl) serve as PSII analogs in the active layer.
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