Implant-Based Breast Reconstruction following Infected Device Explantation: Is a Second Attempt Worth It?

Plast Reconstr Surg

From the Department of Plastic and Reconstructive Surgery, The University of Texas M. D. Anderson Cancer Center, and The University of Texas, McGovern Medical School.

Published: August 2022

AI Article Synopsis

  • - The study investigates outcomes of second implant-based breast reconstructions after infections led to the removal of the first devices, analyzing data from over 6,000 surgeries between 2006 and 2019.
  • - Out of 298 infected cases, 83 patients received 92 second implants, with a notable 36% experiencing postoperative complications, primarily infections (25%), and significantly higher infection rates for second attempts compared to first attempts.
  • - Despite a high overall success rate of 88% for cases without prior radiation or device exchange, patient satisfaction regarding breast appearance and sexual well-being was lower for second attempts, highlighting the risks and the need for realistic expectations for patients considering repeat surgeries.

Article Abstract

Background: Infection is a dreaded complication of implant-based breast reconstruction. There is a paucity of literature on the outcomes of a secondary reconstruction after infected implant-based breast reconstruction explantation.

Methods: The authors conducted a retrospective study of patients who underwent a second implant-based breast reconstruction following a failed infected device between January of 2006 and December of 2019. Surgical and patient-reported outcomes (BREAST-Q) were collected and analyzed.

Results: A total of 6093 implant-based breast reconstructions were performed during the study period, 298 (5 percent) of which involved device removal because of infection. Eighty-three patients ultimately received 92 second-attempt breast implants. Thirty-six percent of cases developed at least one postoperative complication, with infection [23 breasts (25 percent)] being the most common. Compared with first-attempt implant-based breast reconstruction, we found significantly higher infection rates among second-attempt cases (9 percent and 21 percent, respectively; p = 0.0008). Patient-reported satisfaction with the breast and sexual well-being were lower after second-attempt than after first-attempt implant-based breast reconstruction ( p = 0.018 and p = 0.002, respectively) reported in the literature. Mean follow-up was 41 ± 35 months. If we exclude patients with prior radiation therapy and those who received device exchange, the success rate is 88 percent.

Conclusions: It is reasonable to offer women second-attempt implant-based breast reconstruction after explantation because of infection. However, this patient population has a higher infection and explantation rate and lower patient-reported satisfaction than patients undergoing first-attempt implant-based breast reconstruction. Because of these increased surgical risks and elevated complication rates, patients must be given reasonable expectations during preoperative discussions and when providing informed consent for second-attempt implant-based breast reconstruction.

Clinical Question/level Of Evidence: Risk, III.

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Source
http://dx.doi.org/10.1097/PRS.0000000000009289DOI Listing

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