AI Article Synopsis

  • Atrial fibrillation (AF) frequently recurs after catheter ablation (CA), with an annual recurrence rate of 5%-9%, prompting research into potential predictors of this recurrence.
  • This study evaluated the left atrial appendage (LAA) emptying velocity via echocardiogram in 303 patients post-CA, finding that a velocity of ≥52.3 cm/s is linked to a lower chance of AF recurrence.
  • The results suggest that measuring LAA emptying velocity before the procedure can be a useful tool for predicting AF recurrence outcomes in patients undergoing CA.

Article Abstract

Background: Recurrence of atrial fibrillation (AF) after catheter ablation (CA) remains common and studies have shown about 5%-9% annual recurrence rate after CA. We sought to assess the echocardiogram derived left atrial appendage (LAA) emptying velocity as a predictor of AF recurrence after CA.

Objective: To determine if LAA emptying is a marker of recurrence of AF post-CA METHODS: A total of 303 consecutive patients who underwent CA for AF between 2014 and 2020 were included. Baseline clinical characteristics and echocardiographic data of the patients were obtained by chart review. LAA emptying velocities were obtained from transesophageal echocardiogram (TEE). LA voltage was obtained during the mapping for CA. Chi-square test and nominal logistic regression were used for statistical analysis. An receiver operator characteristic curve was used to determine LAA velocity cut-off.

Results: Mean patient age was 61.7 ± 10.5; 32% were female. Mean LAA emptying velocity was 47.5 ± 20.2. A total of 103 (40%) patients had recurrence after CA. In the multivariable model, after adjusting for potential confounders, LAA emptying velocity of ≥52.3 was associated with decreased AF recurrence postablation (odds ratio [OR]: 0.55; 95% confidence interval  [CI]: 0.31-0.97; p = .03*). There were 190 (73%) patients in normal sinus rhythm during TEE and CA, and sensitivity analysis of these patients showed that LAA velocity ≥52.3 remained associated with decreased AF recurrence (OR: 0.35; 95% CI: 0.15-0.82; p = .01*).

Conclusion: LAA emptying velocity measured during preprocedural TEE can serve as a predictor of AF recurrence in patients undergoing CA.

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Source
http://dx.doi.org/10.1111/jce.15580DOI Listing

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