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Eyes as Windows: Unveiling Neuroinflammation in Multiple Sclerosis via Optic Neuritis and Uhthoff's Phenomenon.
Diagnostics (Basel)
October 2024
Clinical Neurosciences Department, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
: This study investigated the frequency and timing of optic neuritis (ON) episodes in relation to the onset of multiple sclerosis (MS) and examined the occurrence of Uhthoff's phenomenon and Lhermitte's sign to understand their roles in early diagnosis and disease progression. : A longitudinal study was conducted with 127 MS patients. Clinical data, including ophthalmological examinations for ON, were collected and questionnaires assessed the presence of Uhthoff's phenomenon and Lhermitte's sign.
View Article and Find Full Text PDFVoriconazole-induced central nervous system toxicity: a pharmacovigilance study based on FDA adverse event reporting system (FAERS) database.
Expert Opin Drug Saf
October 2024
Beijing You'an Hospital, Capital Medical University, Beijing, China.
Background: This study aims to evaluate the relationship between voriconazole (VRC) and central nervous system (CNS) toxicity based on the real world data.
Research Design And Methods: The reports of FAERS from January 2004 to March 2022 were included in our study. The CNS toxicity events were identified by using Medical Dictionary for Regulatory Activities terms.
Ophthalmic, systemic, and genetic characteristics of patients with Wolfram syndrome.
Eur J Ophthalmol
September 2020
Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Purpose: To evaluate the ophthalmic, systemic, and genetic characteristics of patients with Wolfram syndrome.
Methods: In total, 13 patients with suspected or clinically diagnosed Wolfram syndrome underwent ophthalmic and systemic examinations and genetic analyses for Wolfram syndrome between August and October 2018.
Results: The mean age of the subjects was 24.
Changes in artistic style after minor posterior stroke.
J Neurol Neurosurg Psychiatry
June 2005
Department of Neurology, Lausanne University Hospital, CH 1011 Lausanne, Switzerland.
Background: Two professional painters experienced significant changes in their art as the main consequence of minor stroke located in the left occipital lobe or thalamus.
Methods: The features of this artistic conversion were analysed on the basis of extensive neurological, neuropsychological, and psychiatric evaluations.
Results: Both painters, initially unaware of the artistic changes, exhibited mild signs of executive dysfunction, but no general cognitive decline.
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